research A computational modelling framework to quantify the effects of passaging cell lines
Cell characteristics change with passage numbers, affecting experiment results.
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30 / 1000+ results research A computational modelling framework to quantify the effects of passaging cell lines
Passage numbers affect cell growth and experiment results.
research Regenerative medicine meets mathematical modelling: developing symbiotic relationships
Mathematical modeling can improve regenerative medicine by predicting biological processes and optimizing therapy development.
research Fibroblast state switching orchestrates dermal maturation and wound healing
Fibroblast state switching is crucial for skin healing and development.
research 3D Bioprinting Skin Equivalents: A Methodological Perspective on Human Keratinocyte and Fibroblast Models for Wound Repair and Regeneration
3D bioprinting shows promise for creating skin substitutes, but standardized methods are needed for clinical use.
research Modeling cell–cell communication for immune systems across space and time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
research Homology Modeling of 5-alpha-Reductase 2 Using Available Experimental Data
Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.
research Molecular modeling and structural characterization of a high glycine–tyrosine hair keratin associated protein
The 3D structure of a key hair protein was modeled, revealing specific helical structures and stabilization features.
research Molecular modeling of hair keratin/peptide complex: Using MM‐PBSA calculations to describe experimental binding results
Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.
research Discovery of novel 5α-reductase type II inhibitors by pharmacophore modelling, virtual screening, molecular docking and molecular dynamics simulations
A new compound may treat benign prostatic hyperplasia better than finasteride.
research Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Modeling Oxidative Stress–Linked Telogen Effluvium: A Monte Carlo Simulation Using Published Trichoscopy Norms and Cannabis Exposure Distributions
Higher cannabis use may be linked to more severe hair loss.
research How a reaction-diffusion signal can control spinal cord regeneration in axolotls: A modeling study
Axolotl spinal cord regeneration may be controlled by a specific signal affecting cell sensitivity and diffusion.
research How a reaction-diffusion signal can control spinal cord regeneration in axolotls: A modelling study
Axolotls regenerate their spinal cord through a signal that recruits cells, influenced by cell sensitivity and signal spread.
research Foundations of Bayesian Networks
Bayesian networks are tools for modeling variables' probabilistic relationships, which can efficiently represent complex probabilities and help in making inferences.
research Hair keratin molecular dynamics models
Molecular dynamics simulations help understand keratin's properties and predict hair's response to treatments.
research De Novo Design of Anti-Aging Peptides
New peptides can delay aging and improve cell function.
research Touch Receptors Undergo Rapid Remodeling in Healthy Skin
Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
research Contact cooling of the skin
Skin can be cooled quickly and safely during laser treatments to protect it without affecting deeper layers.
research High-content drug screening for rare diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research Capsaicin: an in-depth review of its chemical properties, health benefits, and challenges in food applications
Capsaicin offers health benefits and flavor but faces challenges in food use.
research Role of DNA Methylation in the Pathogenesis of Skin Disorders: Mechanisms, Inhibitors of Methylation‐Related Enzyme, and Molecular Docking Studies
Targeting DNA methylation can help treat skin disorders and cancers.
research Stem cells, organoids and their applications for human diseases: Special issue of BMB Reports in 2023
Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.
research Modeling Oxidative Stress-Linked Telogen Effluvium Using Monte Carlo Simulation of Published Trichoscopy Norms and Cannabis Exposure Distributions
Higher cannabis exposure may lead to increased hair loss.
research Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances
The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
research A regulatory perspective on pharmacokinetic/pharmacodynamic modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research Thermodynamic Modeling of the Gas-Antisolvent (GAS) Process for Precipitation of Finasteride
The Gas-Antisolvent process can be effectively modeled and optimized to create Finasteride, a hair growth drug.
research Mathematical Modeling of Alopecia Areata: Unraveling Hair Cycle Dynamics, Disease Progression, and Treatment Strategies
The model helps understand alopecia areata and suggests treatment strategies.
research Mathematical Modeling of Alopecia Areata: Unraveling Hair Cycle Dynamics, Disease Progression, and Treatment Strategies
The model helps understand alopecia areata and suggests better treatment strategies.
research Computational screening of repurposed drugs and natural products against SARS-Cov-2 main protease (Mpro) as potential COVID-19 therapies
Some existing drugs and natural products might work against COVID-19 by targeting the virus's main protease.