134 citations
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December 2018 in “Dermatology and Therapy” Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.
130 citations
,
August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
125 citations
,
August 2020 in “Frontiers in Immunology” Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
118 citations
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January 2016 in “Current Topics in Developmental Biology” The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
110 citations
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July 2010 in “Journal of The American Academy of Dermatology” Hair loss linked to higher heart disease risk in both men and women.
108 citations
,
October 2004 in “Anesthesiology” Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.
100 citations
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July 2018 in “Journal of The American Academy of Dermatology” People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.
87 citations
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May 2012 in “PLOS Genetics” Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.
85 citations
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August 2018 in “Psychological Medicine” Women with PCOS are more likely to suffer from depression, anxiety, and stress.
75 citations
,
September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
73 citations
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January 2013 in “Annals of Dermatology” People with hair loss, especially those with certain types, have lower zinc levels, and zinc supplements might help.
72 citations
,
January 2011 in “Current Pharmaceutical Design” S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
68 citations
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February 1990 in “Journal of Applied Social Psychology” Bald men are often viewed more negatively and as older than they really are.
66 citations
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March 2019 in “Cellular and Molecular Life Sciences” Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
65 citations
,
July 2006 in “Journal of biological chemistry/The Journal of biological chemistry” The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.
64 citations
,
May 2003 in “Journal of health psychology” Women with excess body hair feel psychological distress influenced by societal beauty standards, but distress isn't directly linked to the amount of hair.
60 citations
,
December 2013 in “PLoS ONE” EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.
59 citations
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November 2018 in “Psychoneuroendocrinology” Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
58 citations
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March 2013 in “Human Reproduction Update” Products should be called 'sperm-safe' only after thorough, well-designed tests.
55 citations
,
May 2014 in “Journal of feline medicine and surgery” Combining systemic and topical treatments, guided by weekly fungal cultures, effectively treats cat ringworm.
51 citations
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November 2018 in “JAMA Dermatology” PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.
50 citations
,
September 2016 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.
46 citations
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December 2014 in “Journal of The American Academy of Dermatology” Premature hair graying in young men is linked to family history, obesity, and smoking.
45 citations
,
February 2019 in “Journal of Affective Disorders” Melatonin improved mental health and metabolism in women with PCOS.
43 citations
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November 2018 in “Nature Communications” Genetic variations affecting skin structure play a key role in severe acne.
38 citations
,
February 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
37 citations
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June 2021 in “Journal of the European Academy of Dermatology and Venereology” Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
32 citations
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February 2014 in “Psychopharmacology” Dutasteride makes alcohol less sedating and may lead to less drinking in men.
31 citations
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September 2015 in “BJUI” Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.