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research PD59-09 PHOSPHODIESTERASE INHIBITORS COULD REVERSE THE PROLIFERATION OF BPH EPITHELIAL CELLS INDUCED BY CD8+ T CELLS IN LOW ANDROGEN CONDITION

April 2018 in “The Journal of Urology”

Phosphodiesterase inhibitors like tadalafil can reduce cell growth in BPH caused by CD8+ T cells in low androgen conditions.

Minoxidil Exerts Different Inhibitory Effects on Gene Expression of Lysyl Hydroxylase 1, 2, and 3: Implications for Collagen Cross-Linking and Treatment of Fibrosis

research Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: Implications for collagen cross-linking and treatment of fibrosis

38 citations , June 2005 in “Matrix Biology”

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors

20 citations , March 2005 in “Current Medicinal Chemistry”

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

research Anti-Androgen Drugs in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review

1 citations , December 2019 in “Current Medicinal Chemistry”

Anti-androgen drugs can help reduce OCD symptoms, but more large-scale trials are needed to confirm their effectiveness.

research Recombinant Human Annexin A5 Ameliorates Localized Scleroderma by Inhibiting the Activation of Fibroblasts and Macrophages

July 2025 in “Pharmaceutics”

Recombinant Human Annexin A5 may help treat localized scleroderma by reducing skin thickening and inflammation.

research Actions of isotretinoin and etretinate on the pilosebaceous unit

46 citations , April 1982 in “Journal of the American Academy of Dermatology”

Isotretinoin shrinks sebaceous glands without affecting hair or skin color, unlike etretinate.

research LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.

53 citations , June 1993 in “Proceedings of the National Academy of Sciences of the United States of America”

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Alpha-1 Adrenergic Receptor Agonist Induced Piloerection Protects Against the Development of Traction Alopecia

research α₁-AR agonist induced piloerection protects against the development of traction alopecia

5 citations , December 2015 in “Dermatologic Therapy”

Using a certain drug on the skin can help prevent hair loss caused by pulling on the hair.

research Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice

42 citations , August 2012 in “Psychoneuroendocrinology”

Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.

research Minoxidil therapy in children with severe hypertension

54 citations , May 1977 in “The Journal of Pediatrics”

Minoxidil helps lower high blood pressure in kids, but can cause fluid retention and hair growth.

research Neuroactive steroids inhibit spinal reflex potentiation by selectively enhancing specific spinal GABAA receptor subtypes

44 citations , February 2009 in “Pain”

Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.

research Expression of estrogen, androgen, and glucocorticoid receptors in recent striae distensae

67 citations , December 2009 in “International Journal of Dermatology”

Hormonal changes in skin may cause stretch marks.

research Method of chest compression for infants in a single rescuer; evaluation of chest compression technique and new device

September 2017

Stroma structural changes cause large pores and skin laxity, regardless of age or ethnicity.

research Treatment of Severe Hypertension with Minoxidil: Advantages and Limitations

37 citations , April 1979 in “The Journal of Clinical Pharmacology”

Minoxidil effectively controls blood pressure but side effects may limit its use.

research LB1027 Identifying the mechanism of tension-associated tissue fibrosis based on single cell RNA sequencing on keloid scar

July 2024 in “Journal of Investigative Dermatology”

Mechanical tension worsens keloid scars by activating inflammation and fibrosis pathways.

research Effects of androgen deprivation on chronic bacterial prostatitis in a rat model

38 citations , August 2003 in “International Journal of Urology”

Finasteride and levofloxacin effectively reduce chronic bacterial prostatitis severity.

research CUTANEOUS SIDE-EFFECTS OF BETA-ADRENERGIC BLOCKERS

22 citations , April 1985 in “Australasian Journal of Dermatology”

Beta-blockers can cause rare skin side-effects, which usually improve after stopping the medication.

research Chapter 17. Selective androgen receptor modulators (SARMs)

18 citations , January 2001 in “Annual Reports in Medicinal Chemistry”

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.