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Coats' Plus: A Progressive Familial Syndrome of Bilateral Coats' Disease, Characteristic Cerebral Calcification, Leukoencephalopathy, Slow Pre- and Post-Natal Linear Growth, and Defects of Bone Marrow and Integument

research Coats' Plus: A Progressive Familial Syndrome of Bilateral Coats' Disease, Characteristic Cerebral Calcification, Leukoencephalopathy, Slow Pre- and Post-Natal Linear Growth and Defects of Bone Marrow and Integument

80 citations , March 2004 in “Neuropediatrics”

Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

research Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia

77 citations , June 2007 in “PLoS ONE”

Birds can regenerate inner ear cells using specific gene pathways, unlike mammals.

research Induction of dark keratinocytes by 12-O-tetradecanoyl-phorbol-13-acetate and mezerein as an indicator of tumor-promoting efficiency

77 citations , January 1980 in “Carcinogenesis”

TPA is about 50 times more effective at promoting tumors than MZ.

research Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation

76 citations , February 2021 in “International Journal of Molecular Sciences”

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Polymeric Nanocapsular Baicalin: Chemometric Optimization, Physicochemical Characterization, and Mechanistic Anticancer Approaches on Breast Cancer Cell Lines

research Polymeric nanocapsular baicalin: Chemometric optimization, physicochemical characterization and mechanistic anticancer approaches on breast cancer cell lines

76 citations , July 2019 in “Scientific Reports”

Baicalin nanocapsules greatly enhance its anticancer effects on breast cancer cells.

research Stem cells in tissues, organoids, and cancers

76 citations , July 2019 in “Cellular and Molecular Life Sciences”

Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.

research Acne and Systemic Disease

76 citations , November 2009 in “Medical Clinics of North America”

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

research Repurposing of approved cardiovascular drugs

73 citations , September 2016 in “Journal of Translational Medicine”

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders

72 citations , January 2011 in “Current Pharmaceutical Design”

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

research Treatments for Androgenetic Alopecia and Alopecia Areata

72 citations , January 2001 in “Drugs”

Minoxidil and finasteride treat hair loss; more research needed for other options.

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