October 2020 in “Проблемы эндокринологии” Men with higher androgen levels may have severe COVID-19 symptoms, but those on antiandrogen therapy are less likely to contract the virus and have milder symptoms. Anti-androgen drugs could potentially treat COVID-19, but more research is needed.
33 citations
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December 2012 in “NMR in Biomedicine” Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.
22 citations
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July 2019 in “PLOS ONE” Skin lymphatic vessels are essential for hair growth.
555 citations
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July 2001 in “Genes & Development” Tcf3 and Lef1 are key in deciding skin stem cell roles.
375 citations
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July 2006 in “Journal of Investigative Dermatology” Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
314 citations
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April 2010 in “Developmental Cell” β-catenin in the dermal papilla is crucial for normal hair growth and repair.
215 citations
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March 2011 in “Clinical Cancer Research” Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.
197 citations
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January 2019 in “Neuropsychopharmacology” Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
193 citations
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February 2015 in “Nature Communications” Fungi-produced compounds can change plant root growth.
192 citations
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March 2017 in “Cell host & microbe” Hair follicle development and microbes help regulatory T cells gather in newborn skin.
173 citations
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May 2001 in “Human reproduction update” Oestrogens are key for bone growth during puberty in both boys and girls.
160 citations
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January 2014 in “Seminars in cell & developmental biology” Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
156 citations
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January 1989 in “Genes & Development” Keratin expression reflects cell organization and differentiation, not causes it.
149 citations
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June 2002 in “Veterinary record/The veterinary record” Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.
134 citations
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February 2005 in “Neuropsychopharmacology” GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.
123 citations
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May 2009 in “Journal of Neuroscience” In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.
118 citations
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May 2003 in “Toxicological Sciences” Exposure to finasteride in the womb caused lasting reproductive issues in male rats.
115 citations
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February 2016 in “Nature Communications” Epidermal β-catenin activation changes the dermis by signaling different fibroblast types.
104 citations
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March 2014 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” DHT may increase the risk of heart disease and death in elderly men.
98 citations
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December 2008 in “Journal of Investigative Dermatology” Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
95 citations
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July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
88 citations
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January 2004 in “Journal of Neuroscience” Neurosteroids regulate synaptic inhibition in the spinal cord and may help manage spinal pain.
80 citations
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April 2011 in “Plant physiology” White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.
73 citations
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January 2013 in “Annals of Dermatology” People with hair loss, especially those with certain types, have lower zinc levels, and zinc supplements might help.
71 citations
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August 2019 in “The journal of sexual medicine” Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.
67 citations
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December 2019 in “PloS one” Beta-caryophyllene helps improve wound healing in mice, especially in females.
67 citations
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February 2010 in “Acta Obstetricia et Gynecologica Scandinavica” Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.
66 citations
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January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
65 citations
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May 2017 in “Advances in wound care” Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.
62 citations
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September 2014 in “PLoS ONE” Acne-affected skin has more inflammation-related proteins and bacteria than healthy skin.