247 citations
,
August 2011 in “European Journal of Epidemiology” The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.
207 citations
,
April 2006 in “Journal of The American Academy of Dermatology” Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.
182 citations
,
November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
151 citations
,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
138 citations
,
June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
112 citations
,
November 2023 in “Nano-Micro Letters” Nanozymes show promise for effective and safe cancer treatment.
95 citations
,
February 2018 in “Dermatology and Therapy” Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.
81 citations
,
July 2008 in “The Journal of Clinical Endocrinology and Metabolism” Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
68 citations
,
September 2018 in “Trends in Cell Biology” Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.
52 citations
,
September 2020 in “Cell Death and Disease” Overactive sonic hedgehog signaling worsens uterine scarring by reducing cell recycling.
52 citations
,
November 2013 in “European Journal of Pharmaceutical Sciences” Chitosan-decorated polymersomes improve finasteride delivery for hair loss treatment.
50 citations
,
December 2020 in “Bioactive Materials” Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.
40 citations
,
April 2018 in “Endocrine” PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
36 citations
,
September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
34 citations
,
April 2014 in “Psychopharmacology” Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
34 citations
,
December 2012 in “Indian Journal of Dermatology, Venereology and Leprology” Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.
28 citations
,
March 2017 in “Endocrinology” Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
25 citations
,
May 2020 in “EMBO reports” Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
25 citations
,
June 2018 in “Journal of The American Academy of Dermatology” Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
21 citations
,
November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
21 citations
,
December 2011 in “Chungara” Mummy hair's chemical composition may not accurately show ancient people's health due to environmental contamination.
20 citations
,
September 2005 in “Clinics in Dermatology” Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.
18 citations
,
September 2021 in “Journal of Neuroendocrinology” Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
18 citations
,
January 2015 in “Data series” Hurricane Sandy increased contamination in estuarine sediments in New Jersey and New York.
16 citations
,
September 2018 in “Journal of Ethnopharmacology” Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
14 citations
,
January 2018 in “Endocrine” Cantú syndrome may be linked to pituitary adenomas.
13 citations
,
December 2020 in “PLoS ONE” Genetic factors influence growth and brain development in children.
12 citations
,
November 2014 in “Bioscience, Biotechnology, and Biochemistry” Genetically modifying a bacteria and changing its growth conditions significantly increased the production of a chemical called dipicolinic acid.
11 citations
,
December 2022 in “Arterial Hypertension” New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.
11 citations
,
January 2012 in “Journal of cell science” Rac1 is essential for proper hair structure and color.