Researchers made a mouse model with curly hair and hair loss by editing a gene.
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November 1959 in “Annals of the New York Academy of Sciences” Hair and wool have complex microscopic structures with microfibrils and varying cystine content.
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July 2000 in “PubMed” Hair has unevenly distributed proteins and lipids, with lipids mainly in the cuticle and proteins in the cortex and medulla.
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November 2015 in “Scientific reports” Human hair has a new region with ordered filaments and the cuticle contains β-keratin sheets.
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March 2017 in “Experimental Dermatology” Curly hair is influenced by specific genetic variations.
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October 1999 in “Archives of Dermatology” Curly hair in certain scalp areas can be an early sign of hair loss.
A 5-year-old girl has sparse, dry, and brittle hair but is otherwise healthy.
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January 2018 in “Acta dermato-venereologica” A teenager's hair with alternating white and dark bands, known as Pili annulati, is a genetic condition that is usually harmless and often considered attractive.
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January 1925 in “Archives of Dermatology” Trichostasis spinulosa is a rare skin condition with hair-filled plugs in hair follicles.
The curly mutation in SELH/Bc mice affects hair and may help study human genetic disorders.
34 citations
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August 1966 in “Experimental cell research” Keratin fibrils in hair form and stop growing at specific points in the follicle.
May 2024 in “Frontiers in medicine” A genetic mutation in the LIPH gene causes tightly curled hair that stops growing in some Japanese individuals.
September 2014 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” OCT can effectively examine and reveal details about human hair and scalp conditions.
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July 2015 in “Journal of Medical Genetics” A genetic variant in the KRT25 gene causes tightly curled hair.
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February 2021 in “FEBS open bio” Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.
April 2019 in “Progress in Crystal Growth and Characterization of Materials” Hair grows like a crystal at a solid-liquid interface without cell division.
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June 2022 in “Tidsskrift for Den norske legeforening” A young boy's uncombable hair is due to a rare genetic condition that usually improves over time.
December 1978 in “Indian Journal of Otolaryngology and Head & Neck Surgery” 254 citations
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January 2007 in “Chemical Society Reviews” Hair is a complex protein fiber with unique properties useful for developing hair products.
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January 1983 in “Elsevier eBooks” Hair grows from living roots, is made of dead keratin, and goes through growth, rest, and shedding stages.
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August 2020 in “Frontiers in Cell and Developmental Biology” Twist1 helps maintain important features of cells crucial for hair growth by working with Tcf4 and β-catenin.
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March 2009 in “Hirosaki University Repository for Academic Resources (Hirosaki University)” Hirosaki hairless rats have sparse, twisted hair due to missing hair keratin genes.
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January 1998 in “Genes & Development” Hoxc13 gene is essential for hair, nail, and papilla development.
September 2016 in “Journal of Dermatological Science” Björnstad syndrome causes twisted hair from birth.
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March 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” The 14-3-3σ gene is essential for preventing hair loss.
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February 1989 in “Journal of Investigative Dermatology”
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October 2020 in “Dermatology Practical & Conceptual” Bubble hair damage is caused by high heat from styling tools, and trichoscopy helps diagnose it.
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July 1973 in “Archives of dermatology” Tight cornrow braids may cause hair loss.
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September 2003 in “CRC Press eBooks” Hair is important for social and sexual communication in humans.
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August 2023 in “Nature Communications” Mouse zigzag hair bends form due to a 3-day cycle of changes in hair progenitors and their environment.