research Wnt Signaling in Skin Development, Homeostasis, and Disease
Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
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research Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications
Stem cells are crucial for skin repair and new treatments for chronic wounds.
research 25 Hydroxyvitamin D 1 α-Hydroxylase Is Required for Optimal Epidermal Differentiation and Permeability Barrier Homeostasis
The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.
research The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research Cell death in the skin
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Liposomes in cosmeceutics
Liposomes could improve how skin care products work but are costly and not very stable.
research Exogen, Shedding Phase of the Hair Growth Cycle: Characterization of a Mouse Model
Researchers found that hair shedding happens mostly when new hair is growing and involves a unique process.
research Delivery and targeting of nanoparticles into hair follicles
Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
research Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development
Fatty acid transport protein 4 is essential for skin and hair development.
research The Conundrum of Skin Pores in Dermocosmetology
Different types of skin pores should be identified correctly and evaluated with suitable methods for reliable results.
research 2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation
TCDD speeds up skin barrier formation by increasing certain gene expressions.
research Follicular and percutaneous penetration pathways of topically applied minoxidil foam
Minoxidil foam enters hair follicles and skin for hair growth.
research The human type I keratin gene family: Characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain
The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.
research Pathways to inflammation: acne pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
research Targeted gene delivery to skin cells in vivo: A comparative study of liposomes and polymers as delivery vehicles
Nonionic liposomes are the best for delivering genes to skin cells.
research Stress-related skin disorders
Stress can worsen skin conditions by affecting hormone levels and immune response.
research Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia
Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
research Role of -catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer
Beta-catenin is crucial for skin cell growth, development, and cancer formation.
research Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia
Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.
research Hair follicles, their disorders and their opportunities
Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
research α3β1-integrin regulates hair follicle but not interfollicular morphogenesis in adult epidermis
α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
research A Unique Clinicopathological Manifestation of Fungal Infection: A Case Series of Deep Dermatophytosis in Immunosuppressed Patients
Early treatment of superficial fungal infections in immunocompromised patients is crucial.
research MicroRNAs in the skin: role in development, homoeostasis and regeneration
MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
research Three-Dimensional Analysis of Cell Division Orientation in Epidermal Basal Layer Using Intravital Two-Photon Microscopy
Cell division orientation varies by body site and is linked to epidermal thickness and cell density.
research Chemotherapy of psoriasis and other skin disorders with oral retinoids
Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.
research Women's midlife health Reframing menopause
The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.
research Developing stratified epithelia: lessons from the epidermis and thymus
The skin and thymus develop similarly to protect and support immunity.
research In situ labeling of DNA reveals interindividual variation in nuclear DNA breakdown in hair and may be useful to predict success of forensic genotyping of hair
In situ DNA labeling in hair can help predict forensic DNA analysis success.
research Thyroid hormone action on skin.
Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.
research Penetration Enhancement of Topical Formulations
New methods improve how well skin treatments work by helping drugs get through the skin barrier.