research Environmental Factors and Puberty Timing: Expert Panel Research Needs
Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.
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research Androgen Therapy in Women: An Endocrine Society Clinical Practice Guideline
The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
research Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention
Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.
research A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men
5% minoxidil works better for hair growth and density, with minor irritation.
research Advances of Non-Ionic Surfactant Vesicles (Niosomes) and Their Application in Drug Delivery
Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.
research Comparative regenerative mechanisms across different mammalian tissues
Understanding different species' regeneration can improve mammalian healing.
research The pathophysiology of polycystic ovary syndrome
Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
research Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair
Wnt1/βcatenin signaling is crucial for heart repair after injury.
research Transforming growth factor-β in stem cells and tissue homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Nutritional factors and hair loss
Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.
research The Rotterdam Study: 2010 objectives and design update
The Rotterdam Study aims to understand various diseases in older adults.
research The prevalence of polycystic ovary syndrome in a community sample of Iranian population: Iranian PCOS prevalence study
About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.
research Evaluation and treatment of male and female pattern hair loss
Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.
research Lifestyle changes in women with polycystic ovary syndrome
Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.
research Ethnicity, obesity and the prevalence of impaired glucose tolerance and type 2 diabetes in PCOS: a systematic review and meta-regression
Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.
research Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration
Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
research Biology of estrogens in skin: implications for skin aging
Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
research COVID-19 and Sex Differences
Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
research ATP-dependent chromatin remodeling during mammalian development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research Fortnightly review: Male pattern androgenetic alopecia
Hair loss in men is common, treatable, but not curable.
research Fibrinogen and LDL apheresis in treatment of sudden hearing loss: a randomised multicentre trial
Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.
research Androgenetic alopecia: pathogenesis and potential for therapy
Hair loss needs more research for better treatments.
research Wound Healing and the Use of Medicinal Plants
Some medicinal plants can help heal wounds and may lead to new treatments.
research Endocrinology of Transgender Medicine
Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
research Testosterone therapy for transgender men
Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.
research Metabolic risk in PCOS: phenotype and adiposity impact
Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.
research DrugNet: Network-based drug–disease prioritization by integrating heterogeneous data
DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.
research Cost-effectiveness of palliative chemotherapy in advanced gastrointestinal cancer
Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research K ATP Channels and Cardiovascular Disease
K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.