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research The structure of human trichohyalin : potential multiple roles as a functional ef-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein

2 citations , January 1993

Trichohyalin is a versatile protein involved in hair and skin structure.

research Biochemical Evidence That Small Proline-rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes

99 citations , May 1998 in “Journal of biological chemistry/The Journal of biological chemistry”

Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.

research Structures of three polycystic kidney disease-like domains fromClostridium histolyticumcollagenases ColG and ColH

18 citations , February 2015 in “Acta Crystallographica Section D: Structural Biology”

The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.

research A Novel Marker of Tissue Junctions, Collagen XXII

226 citations , May 2004 in “Journal of Biological Chemistry”

Collagen XXII is a marker for tissue junctions, aiding in structural integrity and found in muscles, heart, skin, and arthritic joints.

research Glypican-1, -4 and 6 Participate in the Hair Follicle Stem Cell Differentiation via Specific Interactions with BMP2R, Fz7 and Patched 1

October 2024 in “SPIRE - Sciences Po Institutional REpository”

research Trichohyalin: A structural protein of hair, tongue, nail, and epidermis

27 citations , July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”

research 547 CDK9 Kinase Activation in Association with AFF1-SEC Initiate Epidermal Progenitor differentiation

November 2022 in “Journal of Investigative Dermatology”

NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.

research Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations

36 citations , March 2014 in “Cell death and differentiation”

Disrupting β-catenin signaling in certain cells causes anorectal malformations.

research Corticotropin-releasing hormone inhibits autophagy by suppressing PTEN to promote apoptosis in dermal papilla cells

April 2025 in “Annals of Medicine”

CRH can cause hair loss by promoting cell death in hair growth cells.

Single-Cell Transcriptomics Reveals Hair Growth Retardation Mediated by Aberrant Connective Tissue Sheath Contraction in Male Androgenetic Alopecia

research Single-cell transcriptomics reveals hair growth retardation mediated by aberrant connective tissue sheath contraction in male androgenetic alopecia

February 2026 in “Nature Communications”

Inhibiting connective tissue sheath contraction may improve hair growth in male pattern baldness.

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