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December 2016 in “PloS one” A specific protein in chicken embryos links early skin layers to feather development.
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December 2022 in “Biomolecules & therapeutics” Minoxidil may help reduce aging effects in brain cells.
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January 1989 in “Genes & Development” Keratin expression reflects cell organization and differentiation, not causes it.
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July 2005 in “Genetics” Key genes are crucial for Drosophila wing development and could be insecticide targets.
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November 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.
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August 2013 in “Journal of experimental botany” Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.
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August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
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June 2017 in “Nature Communications” A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
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February 1996 in “Journal of biological chemistry/The Journal of biological chemistry” The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.
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December 1999 in “Mechanisms of Development” Whn is crucial for hair growth in certain areas by controlling a specific gene.
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.
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August 2014 in “Wiley interdisciplinary reviews. Developmental biology” The skin and thymus develop similarly to protect and support immunity.
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May 1994 in “Journal of Investigative Dermatology” Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
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August 2018 in “BMC Genomics” The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.
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December 2011 in “Annals of anatomy” Involucrin helps strengthen the inner parts of human hair.
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April 1996 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.
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January 1979 in “International review of cytology” Wool follicles are complex, involving interactions between different cell types and structures.
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April 2001 in “Current Biology” c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
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January 2002 in “Mechanisms of development” Different enzymes are active in different parts of developing mouse organs.
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August 2016 in “Development” ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
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June 2015 in “Stem Cell Research & Therapy” Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
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July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
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February 2007 in “Journal of Investigative Dermatology” K39 and K40 are the last keratins expressed in hair development, completing the hair keratin catalog.
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” HOXC13 is essential for hair and nail development by regulating Foxn1.
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August 2002 in “American Journal Of Pathology” Cathepsin L deficiency causes hair and skin issues in mice.
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May 2021 in “Nature Communications” High proliferation and cell delamination drive early skin development, while later stages may not rely on cell division orientation.
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
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January 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.