64 citations
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January 1998 in “Drugs” Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.
62 citations
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December 2015 in “Clinical Medicine” Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).
61 citations
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June 2016 in “Clinical Medicine” PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.
60 citations
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September 2001 in “Journal of the American Academy of Dermatology” Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.
60 citations
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September 1979 in “Fertility and sterility” Spironolactone can reduce hair growth in women with hirsutism.
59 citations
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November 2018 in “Psychoneuroendocrinology” Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
48 citations
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February 2008 in “Nutrition in Clinical Practice” Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.
40 citations
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May 2014 in “PLoS ONE” Chronic stress can reduce skin pigmentation.
40 citations
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April 2013 in “Dermato-endocrinology” People with chronic Alopecia Areata often have lower vitamin D levels.
40 citations
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December 2012 in “Epilepsia” Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
40 citations
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November 2009 in “Experimental Dermatology” The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.
38 citations
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April 2018 in “Psychopharmacology/Psychopharmacologia” Blocking CRF-R1 can reduce alcohol intake in stressed mice.
38 citations
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June 2015 in “Expert Opinion on Therapeutic Targets” Blocking the prolactin receptor might help treat various diseases, but more research is needed.
38 citations
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February 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
34 citations
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September 2020 in “BMC Endocrine Disorders” Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
34 citations
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January 2008 in “International Review of Neurobiology” Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.
33 citations
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December 2023 in “Cell Death Discovery” Cepharanthine may help treat gastric cancer by causing cancer cell death and affecting energy use.
33 citations
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October 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces hair growth and is safe for women with excessive hair.
31 citations
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November 2014 in “Journal of Endocrinological Investigation” Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
31 citations
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January 2014 in “Journal of endocrinological investigation” Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.
30 citations
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March 2001 in “Environmental Health Perspectives” Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.
29 citations
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September 2012 in “Dermatologic Clinics” Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
26 citations
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January 2017 in “Acta dermato-venereologica” Antidepressants might help with skin inflammation and improve conditions like psoriasis and eczema.
26 citations
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April 2007 in “Journal of pediatric gastroenterology and nutrition” A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.
25 citations
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June 2017 in “Molecular and Cellular Endocrinology” Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
24 citations
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September 2001 in “Journal of The American Academy of Dermatology” Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
22 citations
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January 2014 in “Indian Journal of Endocrinology and Metabolism” Family members of North Indian women with PCOS have a high rate of metabolic syndrome.
22 citations
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October 2011 in “Bone” Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
21 citations
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May 2005 in “Journal of the American Veterinary Medical Association” The exact cause of growth hormone-responsive alopecia in dogs is unclear.
21 citations
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November 1981 in “Archives of Dermatology” Ashy dermatosis may be linked to atopy and thyroid disease and can be treated with topical steroids.