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December 2020 The skin is the body's largest organ, with layers, cells, and structures that protect and support it.
Retinoic acid can change skin development, like turning scales into feathers or forming glands.
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December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
Keratinocytes grew and migrated into hair follicle areas but disappeared after 15-20 days.
April 2023 in “Journal of Investigative Dermatology” Ectomesenchyme is a key source of skin stem cells.
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December 1986 in “Journal of Investigative Dermatology” 21 citations
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December 2024 in “Tissue Barriers” The epidermis is the stiffest skin layer.
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September 2005 in “Experimental dermatology” The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
August 2019 in “Journal of Investigative Dermatology” The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.
February 1990 in “PubMed” Hair follicle cells and skin cells differ in keratinization and other features.
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October 2012 in “Journal of Morphology” Reptile skin hardens by layering beta-proteins on keratin.
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June 1990 in “Journal of Investigative Dermatology” January 2024 in “Toxicologic Pathology” The skin protects the body, helps heal wounds, stores energy, and supports health.
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July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
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August 2023 in “Developmental cell” The research maps the complex development of early mouse skin, identifying diverse cell types and their roles in forming skin layers and structures.
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December 1977 in “Virchows Archiv B Cell Pathology” February 2022 in “Cosmetic Dermatology” Healthy skin prevents water loss and protects against threats.
January 2006 in “Elsevier eBooks” Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.
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March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
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September 1980 in “Zoological Journal of the Linnean Society” Dendritic cells help regulate skin development and hair growth in mice.
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February 1968 in “Australian Journal of Zoology” The southern elephant seal's skin layer helps waterproof the skin by being tightly connected to hair shafts.
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January 1991 in “Acta Dermato Venereologica” Basal cell epithelioma-like changes are most similar to normal basal cells.
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May 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
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May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
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January 1994 in “Micron” Mature hair surfaces are formed by keratinized cells with developed layers, not just modified plasma membranes.
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November 2002 in “Journal of Investigative Dermatology” August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Different types of skin cells create unique support structures that can affect skin cell growth and could help in skin repair.
July 2023 in “Research Square (Research Square)” Skin's uneven surface and hair follicles affect its stress and strain but don't change its overall strength, and help prevent the skin from peeling apart.