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research Targeted Knockout of β-Catenin in Adult Melanocyte Stem Cells Using a Mouse Line, Dct::CreERT2, Results in Disrupted Stem Cell Renewal and Pigmentation Defects

3 citations , October 2020 in “Journal of Investigative Dermatology”

Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.

research Murine Hair Follicle Derived Stem Cell Transplantation onto the Cornea Using a Fibrin Carrier

3 citations , January 2018 in “BIO-PROTOCOL”

Hair follicle stem cells can be transplanted onto the eye using a fibrin carrier to help repair eye damage.

research Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions

3 citations , November 2011 in “Small GTPases”

Researchers found that hair follicle stem cells can become squamous cell carcinoma due to Ras activation, which could lead to new treatments.

research Alopecia and drug eruption of the scalp associated with a new beta-blocker, nadolol.

3 citations , February 1985 in “PubMed”

Stopping the beta-blocker nadolol led to quick hair regrowth and improved scalp condition.

research Genetic lineage tracing in skin reveals predominant expression of HEY2 in dermal papilla during telogen and that HEY2⁺ cells contribute to the regeneration of dermal cells during wound healing

2 citations , August 2023 in “Experimental Dermatology”

HEY2+ cells help regenerate skin during wound healing.

research MicroRNA-149-Mediated MAPK1/ERK2 Suppression Attenuates Hair Follicle Stem Cell Differentiation

2 citations , February 2022 in “Human Gene Therapy”

Increasing miR-149 reduces hair follicle stem cell growth and hair development by affecting certain cell growth pathways.

research Dermal Hedgehog Signaling in Papillary Fibroblasts: An Emerging Key Player in Skin Regeneration

2 citations , January 2022 in “Journal of Investigative Dermatology”

Hedgehog signaling in skin cells is crucial for hair growth and skin healing, but needs to be balanced to avoid harmful effects like scarring and cancer.

research Abstract 18: Targeted epidermal ablation of EGFR causes local and systemic inflammation

2 citations , April 2010 in “Cancer Research”

Removing EGFR in skin causes inflammation and abnormal hair growth.

research EBF1 expressed in the dermal papilla regulates hair type and length

1 citations , March 2024 in “Genes & Diseases”

EBF1 controls hair type and length.

research Spreading of Isolated Ptch Mutant Basal Cell Carcinoma Precursors Is Physiologically Suppressed and Counteracts Tumor Formation in Mice

1 citations , December 2020 in “International journal of molecular sciences”

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

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