4 citations
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August 2011 in “The Lancet Oncology” Off-label drug use can be risky and requires careful consideration to ensure patient safety.
22 citations
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June 2005 in “Clinical Oncology” Orlistat might block the body's ability to absorb thyroid medication.
June 2018 in “International Review of Intellectual Property and Competition Law”
Finasteride can reduce prostate cancer risk but may delay diagnosis and cause sexual side effects.
September 2017 in “Journal of Investigative Dermatology” The combination of Stemoxydine® and Resveratrol improves hair density in women with Female Pattern Hair Loss.
3 citations
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October 2011 in “QJM” The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.
November 2023 in “Frontiers in pharmacology” Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.
June 2025 in “British Journal of Dermatology” Denosumab may cause alopecia areata.
December 2024 in “Naunyn-Schmiedeberg s Archives of Pharmacology”
20 citations
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August 2019 in “Expert Opinion on Drug Safety” Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.
124 citations
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January 1993 in “The Prostate” Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
Finasteride reduces prostate size, improves urination, and slows prostate cancer progression.
January 2024 in “Pharmacoepidemiology” Patients with rheumatoid arthritis using tofacitinib had more serious side effects than those with alopecia areata.
October 2025 in “Pharmaceutical Development and Technology” Cubosomal gels enhance skin absorption of cetirizine better than niosomal gels.
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
September 2018 in “The Journal of Urology”
3 citations
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August 2020 in “Urology Journal” Using 5-alpha reductase inhibitors may increase the risk of mild depression.
Finasteride may help prevent prostate cancer, but more research is needed.
5 citations
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January 2018 in “Indian Journal of Dermatology/Indian journal of dermatology” A woman got a skin rash from taking aceclofenac, which went away after she stopped the drug.
September 2023 in “Journal of the American Academy of Dermatology” 6 citations
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August 2021 in “Clinical Epidemiology” Men using 5-alpha reductase inhibitors for prostate issues may have a slightly higher risk of blood clots.
February 2026 in “JAAD International” 13 citations
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November 2016 in “The Journal of urology/The journal of urology” Dutasteride is as safe for the heart as finasteride.
December 2012 in “Canadian Urological Association Journal” 5-alpha reductase inhibitors help treat prostate issues in aging men, but their role in cancer prevention is debated.
February 2020 in “Definitions” 5 Alpha-Reductase Inhibitors reduce the effects of testosterone by blocking its conversion into a stronger form.
2 citations
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January 1984 in “PubMed” Cimetidine does not significantly reduce hair growth in hirsutism.
March 2026 in “Frontiers in Bioscience-Elite” Duloxetine, escitalopram, and finasteride may be effective against bacteria and fungi.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Ritlecitinib may help young adults with severe alopecia areata when ketoconazole doesn't work.
November 2017 in “JAMA internal medicine” Women also use 5α-reductase inhibitors, and their effects differ from men.
18 citations
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December 2005 in “Journal of Medicinal Chemistry” A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.