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The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Vitamin D receptor helps prevent skin cancer and supports skin health.

A new mutation in the HJV gene was found in a young woman with juvenile hemochromatosis, causing unusual symptoms like secondary hypothyroidism.

AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.

Blocking certain immune signals can reduce skin damage from radiation therapy.

Two new gene mutations cause a rare hair disorder.

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

The patient likely has Chrousos syndrome, a rare condition causing insensitivity to glucocorticoids, requiring high-dose dexamethasone treatment.

ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Human hair follicles can produce stress hormones like the body's main stress response system.

Using regulatory T cells and Rapamycin together improves chronic graft-versus-host disease treatment outcomes in mice.

Expressing the human vitamin D receptor in skin cells prevents hair loss in certain mice.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.

Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.

SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.

GPCRs are vital for wound healing by affecting cell growth and immune response.

Lower MC2R expression may contribute to alopecia areata.

A new mutation in the KRT86 gene was found to cause the hair disorder monilethrix in a Han family.

The study created a mouse model to mimic degenerative diseases for testing tissue repair and new therapies.

A genetic marker linked to a type of hair loss was found in most patients studied.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

KGF-1 135 is a stable and effective alternative for treating oral mucositis.

NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.