60 citations
,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
60 citations
,
March 2011 in “Proceedings of the National Academy of Sciences of the United States of America” RANK-RANKL signaling is essential for hair growth and skin health.
56 citations
,
February 2012 in “Cell Cycle” MicroRNAs are crucial for controlling skin development and healing by regulating genes.
54 citations
,
November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” Keratins are important for skin cell health and their problems can cause diseases.
48 citations
,
August 2018 in “Nature Communications” JunB is crucial for maintaining healthy skin and hair follicles.
47 citations
,
September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
45 citations
,
July 2022 in “Frontiers in Pharmacology” Natural products can help heal wounds by affecting key biological pathways.
41 citations
,
August 2015 in “The FASEB Journal” Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.
35 citations
,
July 2022 in “Frontiers in Cell and Developmental Biology” Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.
35 citations
,
January 2006 in “Journal of Dermatological Treatment” Zinc can help with some skin problems, but its effectiveness varies depending on the condition.
33 citations
,
January 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.
32 citations
,
December 2018 in “Cytokine” Type I interferons play a key role in the development of various skin diseases.
28 citations
,
January 2017 in “Indian Dermatology Online Journal” Skin problems like acne, excessive hair growth, and oily skin are common in women with PCOS and can help with early diagnosis.
26 citations
,
May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
25 citations
,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
25 citations
,
January 2011 in “Annals of Dermatology” Erlotinib can cause hair loss as a side effect.
23 citations
,
July 2022 in “Nature Cell Biology” Targeting THY1 can improve skin repair and healing.
23 citations
,
August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
21 citations
,
April 2008 in “Toxicologic Pathology” CI-1033 causes skin lesions in rats, similar to humans, due to EGF receptor inhibition.
20 citations
,
November 2014 in “Developmental Dynamics” Palate formation and skin healing share similar biological processes.
18 citations
,
September 2013 in “Technology” The study introduced a new imaging technology to track skin healing and bone marrow cell activity over time.
16 citations
,
July 2021 in “Histopathology” New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
14 citations
,
January 2023 in “Nature Immunology” iNKT cells help develop and maintain healthy skin in young mice.
14 citations
,
October 2018 in “PloS one” Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
14 citations
,
March 2016 in “Cutaneous and Ocular Toxicology” Synthetic cannabinoid addiction can cause skin problems like acne and hair loss.
14 citations
,
May 2013 in “American Journal of Physiology-endocrinology and Metabolism” Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
13 citations
,
March 2013 in “International Journal of Cosmetic Science” AcSDKP may help prevent skin and hair aging and promote their growth.
12 citations
,
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Laminin 332 is essential for normal skin cell behavior and structure.
10 citations
,
May 2024 in “BioEssays” TRPV3 is important for skin health and could be a target for treating skin diseases.
10 citations
,
February 2021 in “PLoS biology” Corin helps control salt and sweat release in sweat glands.