67 citations
,
July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
59 citations
,
June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
56 citations
,
January 2021 in “Clinical and Experimental Medicine” The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.
56 citations
,
February 2012 in “Cell Cycle” MicroRNAs are crucial for controlling skin development and healing by regulating genes.
49 citations
,
December 2009 in “Journal of Investigative Dermatology” Thyroid function affects skin health, with a complex interaction between the two.
48 citations
,
July 2008 in “Acta Biochimica et Biophysica Sinica” Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
41 citations
,
May 2018 in “Nutrition and healthy aging” Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
40 citations
,
December 2012 in “PLoS ONE” Removing Ctip2 in skin cells causes skin inflammation similar to atopic dermatitis.
38 citations
,
September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
36 citations
,
August 2011 in “Experimental Dermatology” Eccrine sweat gland's clear cells likely cause excessive sweating in hyperhidrosis.
34 citations
,
April 2018 in “EMBO journal” The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
33 citations
,
January 2011 in “Elsevier eBooks” Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.
31 citations
,
July 2017 in “Clinical Science” MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
31 citations
,
October 2013 in “Psychosomatics” Psychotropic medications can cause skin reactions, including severe conditions like SJS and TEN, and it's important for psychiatrists to recognize and manage these side effects.
30 citations
,
June 2014 in “Seminars in Immunology” Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
30 citations
,
October 2013 in “Lupus” Hair loss in lupus is different from hair loss in alopecia areata and may indicate lupus activity.
29 citations
,
July 2014 in “PloS one” Meis1 is crucial for skin health and tumor development.
29 citations
,
November 2013 in “Expert Review of Dermatology” Sensitive skin often causes discomfort, affects many people, especially women and older adults, and should be managed with careful product selection.
29 citations
,
December 2012 in “Fibrogenesis & Tissue Repair” Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
28 citations
,
February 2019 in “Genes” Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
24 citations
,
October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
23 citations
,
January 2017 in “Current Rheumatology Reports” Unique fat cells near fibrotic areas contribute to systemic sclerosis progression.
21 citations
,
November 2009 in “Dermatologic Clinics” The document suggests that certain protein deficiencies and scalp blistering in Epidermolysis Bullosa may cause hair loss.
20 citations
,
July 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” Green tea may help with skin health and protect against UV damage, but more research is needed to confirm its safety and effectiveness.
20 citations
,
July 2013 in “PLoS ONE” Targeting EGFR may help reduce hair loss from chemotherapy.
20 citations
,
January 2013 in “Cell & Bioscience” Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
18 citations
,
June 2017 in “Journal of The American Academy of Dermatology” Trichoscopy helps diagnose frontal fibrosing alopecia, even with unusual patterns.
18 citations
,
October 2015 in “Journal of the European Academy of Dermatology and Venereology” European dermatological guidelines vary in quality, with some highly rated, but improvements are needed in applicability and consistency.
14 citations
,
August 2022 in “Lupus Science & Medicine” SLE patients experience two patterns of non-inflammatory symptoms: intermittent and persistent.
12 citations
,
January 1984 in “Clinics in Dermatology” The document concludes that syphilis has varied symptoms that are often missed, making clinical awareness crucial for diagnosis.