November 2022 in “Journal of Investigative Dermatology” Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.
104 citations
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July 1994 in “The Journal of Cell Biology” Basonuclin helps keratinocytes multiply and prevents them from fully maturing.
40 citations
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December 2012 in “PLoS ONE” Removing Ctip2 in skin cells causes skin inflammation similar to atopic dermatitis.
2 citations
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December 2016 in “Experimental cell research” The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
207 citations
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September 1973 in “Entomologia Experimentalis et Applicata” B-type hairs on female butterfly legs help them choose where to lay eggs.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research found that specific stem cells maintain skin gland openings and that disrupting their activity can cause blockages or early cancer signs, indicating a need for targeted treatments.
17 citations
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August 2014 in “The Anatomical Record” Scaffoldin helps form hard skin structures in chicken embryos.
March 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The dermal sheath's contraction is crucial for hair follicle regression and stem cell relocation.
30 citations
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September 2000 in “Journal of Dermatological Science” Fatty acid composition in human skin, mouth, and hair cells varies with keratinization, and cultured cells show essential fatty acid deficiency.
23 citations
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February 2004 in “British Journal of Dermatology” Keratin in mouse hair follicles is complex and plays specific roles.
98 citations
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December 2015 in “The Journal of Cell Biology” Keratin is crucial for skin barrier formation and affects mitochondrial function.
January 2008 in “Yearbook of Dermatology and Dermatologic Surgery” One type of progenitor cell can maintain normal skin in mice.
6 citations
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January 2015 in “Indian Dermatology Online Journal” PEODDN is a rare skin disorder with limited treatment options, best treated with laser therapy.
7 citations
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December 1970 in “Biochimica et Biophysica Acta (BBA) - Protein Structure” 61 citations
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February 1982 in “Cell and Tissue Research” 107 citations
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May 1999 in “Archives of Dermatological Research” Basal cell carcinoma may start from parts of tiny hair follicles.
12 citations
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September 2013 in “BMC Biophysics” Keratin filaments' elasticity is influenced by their terminal domains and surrounding medium.
52 citations
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February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
16 citations
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June 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.
25 citations
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January 2003 in “Plastic & Reconstructive Surgery” Nail-matrical fibroblasts can make non-nail cells produce hard keratin, useful for nail repair.
13 citations
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January 2010 in “PubMed”
April 2023 in “Journal of Investigative Dermatology” Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.
178 citations
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April 2011 in “Journal of Clinical Investigation” Basal cell carcinomas in mice can start from hair follicle stem cells and other skin cell types, depending on signaling levels.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The STRIPAK complex is crucial for skin cell organization and creating a functional skin barrier.
19 citations
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March 2013 in “Biology Letters” Early tetrapod keratins evolved into toe pad proteins in amphibians and hair proteins in mammals.
25 citations
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November 2015 in “Journal of Dermatological Science” Sebum helps protect human skin from microbes.
4 citations
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November 1968 in “Textile research journal” Hair fibers may have a unique, non-protein sheath not previously identified.
7 citations
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August 2022 in “Nature communications” A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.
13 citations
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January 2002 in “Biochemical and biophysical research communications” Interferon β from hair cells stops the growth of other hair cells.
118 citations
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January 2004 in “European Journal of Cell Biology” Balanced protease activity is crucial for healthy skin and hair development.