41 citations
,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
3 citations
,
April 2019 in “Stem cells international” Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.
19 citations
,
July 2009 in “Clinical and Experimental Dermatology” The study found that long-term sun exposure does not significantly affect follicular plugs on the scalp, and the scalp's appearance is unique compared to other body parts.
5 citations
,
January 2018 in “Skin Pharmacology and Physiology” Curcuma aeruginosa extract lotion significantly reduces underarm hair growth.
21 citations
,
January 2010 in “Skin pharmacology and physiology” Special creams can significantly reduce pollen allergens getting into hair follicles.
30 citations
,
April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
4 citations
,
November 1970 in “PubMed” Mustard oil and unsaturated fatty acids can stop the growth of scalp fungus and prevent it from infecting hair.
February 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Keratin 15 helps keep skin cells in a young, undifferentiated state.
August 2025 in “Biomedicines” Half-siblings with a rare skin condition improved with treatment for a fungal infection, but hair loss remained.
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
2 citations
,
September 2004 in “Experimental Dermatology” Desmosomal adhesion is essential for healthy skin structure and function.
May 2000 in “Journal of Investigative Dermatology” Hedgehog signaling is crucial for hair development, cadherins affect cell adhesion, neutrophils play a role in skin lesions, and BP230 autoantibodies impact skin stability.
48 citations
,
July 1993 in “Archives of Dermatological Research” Merkel cells are abundant in facial vellus hair follicles, especially during the anagen phase.
238 citations
,
October 1994 in “Current opinion in genetics & development” The document concludes that recent research has improved understanding of skin diseases and the balance between cell growth and differentiation in the epidermis.
36 citations
,
December 1991 in “Journal of Dermatological Science” Human nails contain both skin and hair keratins, each needing different extraction methods.
104 citations
,
August 2008 in “Clinics in Dermatology” Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.
168 citations
,
August 2009 in “EMBO molecular medicine” Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
July 2016 in “Dermatologie pro praxi” Espumil foam base allows easy preparation of skin medications for hairy areas.
September 2019 in “Journal of Investigative Dermatology” Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.
22 citations
,
March 1999 in “International Journal of Clinical Practice” Diphencyprone (DCP) is an effective treatment for severe alopecia areata and resistant warts, with some risks.
62 citations
,
June 1993 in “Archives of Dermatological Research” August 2021 in “Indian dermatology online journal” A young boy with a rare skin and nail condition improved significantly with simple topical treatments.
Culturing hair follicles at the air-liquid interface with minoxidil significantly boosts hair growth and preserves the root sheath.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.
11 citations
,
January 2010 in “Current problems in dermatology” Ichthyoses are genetic skin disorders that affect the skin's barrier function.
January 1998 in “Differentiation” Basonuclin is crucial for hair follicle development and cycling in mice.
39 citations
,
January 2016 in “PubMed” Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
8 citations
,
August 1993 in “Colloid & Polymer Science” The observed "toughening" in keratin was actually due to water evaporation, not a real change in keratin.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
1 citations
,
December 2024 in “Tissue Barriers” The epidermis is the stiffest skin layer.