research Dissecting the Roles of Innate Cells in the Skin and Intractable Skin Diseases
Hair follicles regulate immune cells in the skin, and disrupting certain pathways can lead to skin issues and infections.
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990-1000 / 1000+ results research 546 Epidermal growth factor receptor as a key regulator of the immune privilege
EGFR is crucial for preventing hair follicle inflammation and hair loss.
research The Endocrine Function of the Skin: An Analytical Narrative
The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.
research 129 Targeted inhibition of EGFR reduces anti-microbial defense mechanisms at the hair canal
Inhibiting EGFR weakens skin's defense against bacteria.
research Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia
Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
research Woolly Antics between the Sheaths
Lipase H is important for hair follicle function and shaping hair fibers.
research Coexpression of Keratins Characteristic of Skin and Hair Differentiation in Nail Cells
research Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells
Clim proteins are essential for maintaining healthy corneas and hair follicles.
research Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation
N-WASP is essential for healthy skin and preventing inflammation.
research Immunolocalization of Scaffoldin, a Trichohyalin‐Like Protein, in the Epidermis of the Chicken Embryo
Scaffoldin helps form hard skin structures in chicken embryos.