research Expression of dermcidin in sebocytes supports a role for sebum in the constitutive innate defense of human skin
Sebum helps protect human skin from microbes.
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810-840 / 1000+ resultsresearch Human stratified squamous epithelia differ in cellular fatty acid composition
Fatty acid composition in human skin, mouth, and hair cells varies with keratinization, and cultured cells show essential fatty acid deficiency.
research Transcriptional profiling of putative human epithelial stem cells
Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
research A Novel Type II Cytokeratin, mK6irs, is Expressed in the Huxley and Henle Layers of the Mouse Inner Root Sheath
A new protein, mK6irs, is found in specific hair layers and may help understand hair growth and diseases.
research 507 Trial to investigate the role of ATP-sensitive potassium channels (KATPc) in dermal papilla cells (DPCs)
ATP-sensitive potassium channels are important for hair growth.
research Integrated multiomics analysis reveals the molecular features and crucial regulators of hair follicles in yak (Bos grunniens)
Yak hair follicles adapt to cold through specific gene regulation, enhancing cell growth.
research Hair structure anatomy and comparative anatomy1 1Dedicated to the memory of the late Dr. R. E. Rivett whose untimely death prevented his role in co-authorship.
Human hair is complex and grows in cycles starting from embryonic life.
research Keratin-mediated hair growth and its underlying biological mechanism
Keratin injections can promote hair growth by affecting hair-forming cells and tissue development.
research Single cell transcriptomics of human epidermis reveals basal stem cell transition states
Basal stem cells in the skin have distinct types that are crucial for skin structure and health.
research 918 Skin morphogenesis by coupling biochemical-bioelectric signals: Calcium oscillations coordinate dermal cell movement by epidermis-derived SHH signaling during feather bud orientation
Calcium signals and SHH guide the direction of feather growth in chicken skin.
research 1338 Dermal Wnt/β-catenin activation tunably controls hair follicle initiation
Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
research Dermo‐epidermal interactions in reptilian scales: Speculations on the evolution of scales, feathers, and hairs
Reptilian scales, feathers, and hairs evolved from changes in skin cell interactions.
research Molecular and Cellular Characterization of Avian Reticulate Scales Implies the Evo–Devo Novelty of Skin Appendages in Foot Sole
Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.
research A Unique Type I Keratin Intermediate Filament Gene Family is Abundantly Expressed in the Inner Root Sheaths of Sheep and Human Hair Follicles
research Characterization of the exocuticle a‐layer proteins of wool
The outer layer of Merino wool is rich in sulfur proteins, making it resistant to damage.
research An ultrastructural study on corkscrew hairs and cigarette‐ash‐shaped hairs observed by dermoscopy of tinea capitis
Corkscrew and cigarette-ash-shaped hairs in tinea capitis are caused by internal hair degradation and external resistance.
research Novel Tissue Mechanics-Guided Cellular Flows Enable the Evolution of Feather Follicles
Cellular flows and tissue mechanics guide feather follicle formation in birds.
research Epidermal homeostasis: a balancing act of stem cells in the skin
Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
research Trichohyalin-Like Proteins Have Evolutionarily Conserved Roles in the Morphogenesis of Skin Appendages
Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.
research Epidermal stem cell diversity and quiescence
Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function
Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research 1229 Melanocyte cell states defined and visualized in developing mouse skin
Researchers found three types of melanocytes in developing mouse skin, each with different genes and locations.
research Telocytes are a critical source of Wnts essential for hair follicle regeneration
Telocytes, cells with long extensions, are vital for hair growth because they produce Wnt signals, which are necessary for hair follicle regeneration.
research Trichothiodystrophy hair shafts display distinct ultrastructural features
Trichothiodystrophy hair is structurally abnormal with protein and organization issues.
research 1393 Lower proximal cup cells but not bulge stem cells regenerate hair follicles after chemotherapy injury
Lower proximal cup cells, not bulge stem cells, regenerate hair follicles after chemotherapy.
research STUDY ON HAIR FOLLICLE FORMATION INDUED BY DERAMAL PAPILLA CELL
Dermal papilla cells can help form hair follicles and produce hair.
research Deleting keratins to find one
A new keratin gene was found in mice, explaining hair growth.
research A cell polarity protein, aPKCλ, is essential for maintaining hair follicle stem cell quiescence and hair follicle regeneration
The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.
research Differentiation of the sebaceous gland
The exact molecular mechanisms of sebaceous gland function are still unclear.
research Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing
KLF4 is important for maintaining skin stem cells and helps heal wounds.