35 citations
,
January 2006 in “Cancer Research” Mice with extra PKCδ resist chemical-induced skin cancer but not UV-induced.
35 citations
,
January 1990 in “PubMed” Cyclosporin A boosts hair growth in nude mice, but minoxidil does not.
34 citations
,
November 2017 in “Gynecological Endocrinology” A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.
34 citations
,
January 2005 in “Journal of the American Veterinary Medical Association” Cyclosporine A can reduce inflammation in dogs with sebaceous adenitis, but ongoing treatment is needed.
34 citations
,
December 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” Rat vibrissa follicles are useful for studying hair growth cycles, especially the transition from pro-anagen to anagen.
33 citations
,
May 2015 in “JAMA Dermatology” Early detection of specific skin lesions can help identify Birt-Hogg-Dube syndrome and prevent serious complications.
33 citations
,
October 2013 in “Cutaneous and ocular toxicology” Oral cyclosporine can help regrow hair in severe alopecia areata cases.
33 citations
,
February 1990 in “Journal of the American Academy of Dermatology” Topical cyclosporine led to significant hair growth in some men with male pattern baldness.
31 citations
,
October 1992 in “PubMed” A mycobacterial protein shares a similar region with a human skin protein, possibly affecting skin diseases.
30 citations
,
July 2009 in “Experimental and clinical endocrinology & diabetes” Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.
30 citations
,
January 2007 Cyclophosphamide can cause serious short-term and long-term side effects, including increased cancer risk and infertility.
30 citations
,
January 1999 in “Dermatology” Cyclosporine A can help some people with severe alopecia areata regrow hair.
30 citations
,
January 1998 in “Dermatology” Birth control pills and cyproterone acetate can help treat acne in women, especially when linked to hormonal issues.
29 citations
,
March 2015 in “Journal of Investigative Dermatology” Cyclosporine A promotes hair growth and prolongs the active growth phase in human hair follicles, but may work differently than in rodents.
29 citations
,
August 2005 in “Biopolymers” L-cysteine slows down the breaking of bonds in hair due to electrostatic interactions.
28 citations
,
July 2017 in “Expert Review of Anticancer Therapy” Breast cancer patients taking CDK4/6 inhibitors are more likely to experience fatigue, hair loss, and mouth sores.
28 citations
,
November 2013 in “The FASEB journal” Mice with CBS deficiency are healthier on a low-methionine diet.
28 citations
,
December 2011 in “Biocatalysis and biotransformation” PDI helps restore over-bleached hair's strength and structure by attaching special peptides.
28 citations
,
October 2011 in “International Journal of Molecular Medicine” Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.
28 citations
,
January 2005 in “Photochemistry and Photobiology” Protein kinase C epsilon may increase skin cancer risk by affecting nearby cells.
27 citations
,
August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers found new genes involved in hair growth, which could help develop new hair treatments.
27 citations
,
January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
26 citations
,
October 2011 in “International Journal of Biological Macromolecules” Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.
26 citations
,
March 1995 in “Differentiation” A rabbit gene important for hair development was identified and detailed.
26 citations
,
July 1992 in “International Journal of Dermatology” Oral cyclosporine A and prednisolone effectively improved alopecia universalis without side effects.
26 citations
,
January 1992 in “Cancer investigation” N-acetylcysteine and ImuVert can prevent hair loss in rats caused by chemotherapy.
26 citations
,
December 1990 in “Journal of Biological Chemistry” Two specific genes are more active during hair growth in mice.
26 citations
,
December 1981 in “British journal of dermatology/British journal of dermatology, Supplement” Cyproterone acetate reduced hair growth in most hirsute females and made hair softer, thinner, and lighter.
25 citations
,
December 2018 in “Human Molecular Genetics” The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
25 citations
,
December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Targeted cytokine treatments may help with alopecia areata, but more research is needed.