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Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

A new compound was made that might help treat diseases related to male hormones.

A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.

CUX1 boosts sheep hair cell growth and affects curl patterns.

The compound was successfully made and shows potential for treating prostate cancer.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

A mutation in the HOXC13 gene causes hair and nail problems in a Syrian family.

A new mouse gene, Keratin 17n, is mainly found in nail tissue and may explain why mice without Keratin 17 don't have nail issues.

Two new enzymes, PAD-R11 and PAD-R4, were cloned and showed activity, with PAD-R11 resembling epidermal enzymes.

Lowering homocyst(e)ine levels can reverse skin and hair lightening by restoring enzyme activity needed for pigmentation.

A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.

C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.

CTIP2 may help in skin development and maintenance.

Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.

Keratin 17 is important for skin's response to radiation, affecting many genes and cell division.

Standard treatment for congenital erythropoietic porphyria was ineffective over five years.

Ceramide synthase 4 is essential for maintaining skin barrier health.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.

Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

A new protein linked to hair strength was identified, aiding in understanding brittle hair conditions.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

Vitamin C derivative may promote hair growth by activating specific genes.

Efficient enzyme function relies on specific residue interactions and structural coordination.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

Keratin 15 helps maintain skin cell growth and repair.

Cirsium japonicum flower extract increases melanin production and could help treat depigmentation conditions.