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Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

A certain gene variation can affect protein production and is linked to male pattern baldness.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Overexpression of hurpin in mice leads to abnormal skin and higher skin cancer risk.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.

Cyclosporin A promotes hair growth in mice and increases a protein linked to hair growth, but it may not work the same way in humans.

The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.

Ceramide synthase 4 is essential for maintaining skin barrier health.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Cyclophosphamide often causes gastrointestinal issues, hair loss, and low blood cell counts in Chinese patients with autoimmune diseases.

Early diagnosis and treatment of congenital adrenal hyperplasia are crucial to manage symptoms and prevent complications.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Combining ciclosporin and simvastatin can cause severe kidney damage.

High doses of cyclosporine A increase testosterone conversion, possibly boosting hair growth.

Long-term high-dose fluconazole can cause reversible hair loss.

Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.

Combining finasteride with dimethyl-β-cyclodextrin improves its absorption and bioavailability.

Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.

Cyproterone acetate is used for topical treatment of diseases dependent on male hormones.

Different forms of the Vitamin D receptor can impact metabolic and hormone issues in Polycystic Ovary Syndrome.

Researchers found a non-functional sheep keratin gene due to mutations.

Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.

The study found that prescribing patterns for Cyproterone Acetate/Ethinylestradiol in Italy did not significantly change after EMA recommendations.