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Quick, selective detection of tadalafil and finasteride in human plasma developed.

CPK1 helps root hair growth in Arabidopsis by activating channels for calcium signaling.

A new gene mutation causes vitamin D resistance and rickets, treatable with calcium therapy.

Some prostate cancers have gene changes that may affect treatment with certain drugs.

CTIP2 may help in skin development and maintenance.

A new genetic mutation was found causing hair and eye issues in a boy.

Most children with a common hemochromatosis genotype had elevated iron levels but no severe symptoms.

The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

The CTLA-4 gene polymorphism does not affect polycystic ovarian syndrome.

Cyclosporin A, a drug, reduces TGF-β2 expression in skin cells, potentially causing excessive hair growth through a process involving the calcineurin/NFAT pathway.

Cyproterone acetate and ethinylestradiol effectively reduce hirsutism and acne in women.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

Finasteride and dutasteride's effects are mainly due to target binding saturation and slow enzyme turnover.

New genetic variants linked to albinism were found in Pakistani families.

Apraglutide and N-acetylcysteine (NAC) show promise in reducing cytarabine's harmful effects on organs.

Compound 7p shows strong potential as an anticancer agent.

Pygo2 is important for early growth and progression of intestinal tumors, and could be a target for treating cancers with certain mutations.

A rare gene variant causes sexual development issues in siblings, needing personalized treatment.

The C-allele and CC-genotype in the PTPN22 gene lower the risk of alopecia areata.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

A new method accurately measures finasteride levels in blood and shows how the body processes it.

Cyproterone and finasteride reduced hypersexuality but caused serious side effects.

A mutation in the vitamin D receptor causes severe resistance to vitamin D, affecting bone health but not hair growth.

Truncating mutations in the C2orf37 gene cause Woodhouse–Sakati syndrome.

A mutation in the HOXC13 gene causes hair and nail problems in a Syrian family.

A man developed severe skin reactions after using a treatment for hair loss.