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Finasteride and dutasteride's effects are mainly due to target binding saturation and slow enzyme turnover.

Mutations in the PADI3 gene may cause central centrifugal cicatricial alopecia in women of African ancestry.

These medications for BPH have known risks and may have new side effects.

Ponatinib can cause a rare skin reaction that resolves with topical treatment and temporary drug discontinuation.

A new method was developed to measure and assess the activity and inhibition of the enzyme steroid 5α-reductase.

Finasteride forms three new products under acidic stress.

Higher SRD5A2 expression predicts better response to finasteride in treating urinary symptoms.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Cepharanthine shows promise as a potential lung cancer treatment by effectively killing cancer cells.

New method effectively analyzes finasteride and its stability.

Genetic variants in CYP genes may worsen PCOS symptoms.

PROTACs show promise in cancer treatment by effectively degrading specific harmful proteins.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Lack of functional CYLD in mice leads to early aging and cancer.

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

Optimized film improves finasteride skin absorption and treatment efficiency.

Cacumen Platycladi oil promotes hair growth better than minoxidil.

Human hair follicles can assess carcinogen metabolism and imidazole compounds might be effective anticarcinogens.

The research helps understand how finasteride works and aids drug development.

PAD enzymes play a key role in hair growth and structure.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.

Created method to measure doxazosin mesylate and finasteride together.

Two methods can measure finasteride and tamsulosin hydrochloride; HPLC is more advantageous, while TLC offers better separation.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Improved finasteride formula allows slow, sustained release and better absorption for patients.

CCL5 is important for the hair growth potential of human dermal papilla cells.

Iron chloride helps create compounds that could be useful in medicine, like treating hair loss.

New mutations in the EBP gene cause CDPX2, affecting bones, skin, eyes, and hair, with females generally less affected than males.