66 citations
,
March 2009 in “British journal of surgery” Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.
66 citations
,
December 2003 in “Endocrinology and Metabolism Clinics of North America” Doctors need to be better prepared to assess and treat obesity in patients.
66 citations
,
January 2000 in “Hormone Research in Paediatrics” Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.
65 citations
,
July 2013 in “International Clinical Psychopharmacology” Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.
64 citations
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May 2003 in “Journal of health psychology” Women with excess body hair feel psychological distress influenced by societal beauty standards, but distress isn't directly linked to the amount of hair.
63 citations
,
May 2017 in “American Journal of Clinical Dermatology” People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.
63 citations
,
March 2011 in “Clinical Endocrinology” Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.
63 citations
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November 1999 in “British journal of dermatology/British journal of dermatology, Supplement” Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
62 citations
,
July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
60 citations
,
May 2011 in “Endocrinology and Metabolism Clinics of North America” Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.
60 citations
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June 1997 in “Drugs & Aging” Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.
59 citations
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July 2020 in “Journal of The American Academy of Dermatology” Oral minoxidil promotes hair growth but may cause side effects; needs monitoring.
59 citations
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May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
59 citations
,
January 2011 in “Retina-the Journal of Retinal and Vitreous Diseases” Finasteride may help treat chronic CSC, improving vision.
59 citations
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September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
59 citations
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August 2007 in “Clinical Endocrinology” The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.
59 citations
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January 2005 in “Endocrine Journal” Sex steroids influence skin appendage function and neoplasm development, with changes in AR and ERalpha in certain gland neoplasms.
59 citations
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February 2003 in “Veterinary Dermatology” Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.
59 citations
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August 1998 in “International Journal of Dermatology” Genetics and hormones cause hair loss; finasteride treats it safely.
58 citations
,
January 2003 in “Thrombosis and Haemostasis” Testosterone may slow down wound healing and increase inflammation.
58 citations
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June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.
58 citations
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October 1993 in “International Journal of Dermatology” Minoxidil helps hair growth and reduces shedding in women.
57 citations
,
January 1986 in “The Prostate” The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
56 citations
,
April 2007 in “Journal der Deutschen Dermatologischen Gesellschaft” Minoxidil works better for female hair loss than alfatradiol, both safe.
56 citations
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April 2015 in “American journal of medical genetics. Part A” Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.
56 citations
,
January 2008 in “Dermatology” Higher iron levels in the blood are not linked to increased hair loss in women.
56 citations
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August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.
56 citations
,
October 1983 in “Archives of Dermatology” Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.
55 citations
,
February 1985 in “Archives of Dermatology” Using minoxidil on the scalp can help grow hair for people with hereditary baldness.
54 citations
,
July 2002 in “Clinical and Experimental Dermatology” DHT, a testosterone byproduct, causes male pattern baldness.