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research Novel Type I Hair Keratins K39 and K40 Are the Last to be Expressed in Differentiation of the Hair: Completion of the Human Hair Keratin Catalog

70 citations , February 2007 in “Journal of Investigative Dermatology”

K39 and K40 are the last keratins expressed in hair development, completing the hair keratin catalog.

research Reciprocal role of vitamin D receptor on β-catenin regulated keratinocyte proliferation and differentiation

49 citations , November 2013 in “The Journal of Steroid Biochemistry and Molecular Biology”

Vitamin D receptor helps control skin cell growth and hair development.

research Characterization of the Promoter Regions of Two Sheep Keratin-Associated Protein Genes for Hair Cortex-Specific Expression

14 citations , April 2016 in “PloS one”

The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.

Differential Expression of Keratin and Keratin-Associated Proteins Linked with Hair Loss in Spontaneously Mutated Inbred Mice

research Differential expression of keratin and keratin associated proteins are linked with hair loss condition in spontaneously mutated inbred mice

July 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

Hair loss in certain mice is linked to changes in keratin-related genes.

research Role of human type II hair keratins in intermediate filament bundling in vitro

October 2015

research Sequence and expression of human hair keratin genes

19 citations , July 1994 in “Journal of Dermatological Science”

Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.

research The Mixed Lineage Kinase Leucine-Zipper Protein Kinase Exhibits a Differentiation-Associated Localization in Normal Human Skin and Induces Keratinocyte Differentiation upon Overexpression

17 citations , November 2000 in “Journal of Investigative Dermatology”

ZPK helps skin cells mature and may affect skin health.

research Genes for intermediate filament proteins and the draft sequence of the human genome

287 citations , July 2001 in “Journal of Cell Science”

The study found 65 intermediate filament genes, including new keratins, and suggested updating keratin naming.

research Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures

15 citations , August 2013 in “Stem Cells and Development”

The method increases stem-like cells for better skin regeneration.

research Serine-rich ultra high sulfur protein gene expression in murine hair and skin during the hair cycle

1 citations , February 1991 in “Journal of Biological Chemistry”

research Keratin 71 Mutations: From Water Dogs to Woolly Hair

11 citations , September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology”

A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.

research Targeted Knockout of β-Catenin in Adult Melanocyte Stem Cells Using a Mouse Line, Dct::CreERT2, Results in Disrupted Stem Cell Renewal and Pigmentation Defects

3 citations , October 2020 in “Journal of Investigative Dermatology”

Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.

research Expression of a truncated form of hHb1 hair keratin in human breast carcinomas

14 citations , December 1998 in “British Journal of Cancer”

Truncated hHb1 keratin may play a role in breast cancer cell transformation.

research In vitro assembly properties of human type I and II hair keratins

1 citations , January 2014 in “Medical Entomology and Zoology”

research The relevance of collagen XVII expression in epidermal differentiation and proliferation

September 2016 in “Journal of dermatological science”

Collagen XVII is crucial for skin cell growth and nail health.

research CtBP1 Overexpression in Keratinocytes Perturbs Skin Homeostasis

9 citations , November 2013 in “Journal of Investigative Dermatology”

Overexpressing CtBP1 in skin cells causes skin and hair problems.

A Discrete Transition Zone Between Cuticle and Cortex Layers of a Human Hair Fiber: Changes Observed in the Presence of Breast Cancer

research A discrete transition zone between cuticle and cortex layers of a human hair fibre: changes observed in the presence of breast cancer

1 citations , October 2017 in “ecancermedicalscience”

Breast cancer alters specific molecular structures in hair, which revert after cancer removal.

research Protein Kinase C Epsilon Signals Ultraviolet Light‐induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism^¶

3 citations , January 2005 in “Photochemistry and Photobiology”

Protein kinase C epsilon may promote skin cancer development after UV exposure by affecting nearby cells.

research A mutation in the type II hair keratin KRT86 gene in a Han family with monilethrix

3 citations , February 2011 in “Journal of Biomedical Research/Journal of biomedical research”

A new mutation in the KRT86 gene was found to cause the hair disorder monilethrix in a Han family.

research The Simplest Protocol for Rapid and Long-Term Culture of Primary Epidermal Keratinocytes from Human and Mouse

2 citations , January 2019 in “Methods in molecular biology”

A new method helps grow skin cells from humans and mice more easily and quickly.

research Efficient In Vitro Transfection of Human Keratinocytes with an Adenovirus-Enhanced Receptor-Mediated System

16 citations , April 2000 in “Journal of Investigative Dermatology”

The AVET system effectively delivers genes to human keratinocytes and may help treat skin diseases.

research Human hair follicle and interfollicular keratinocyte reactivity to mouse HPV16-transformed cells: An in vitro study

9 citations , July 2008 in “Oncology Reports”

HPV16-transformed cells can change human skin cell properties, aiding tumor growth.

research Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes

37 citations , January 2010 in “Human Molecular Genetics”

FTase and GGTase-I are essential for skin keratinocyte health.

research EFFECTS OF HUMAN HAIR KERATIN ALKYLATION ON GROWTH FACTOR DELIVERY AND CELLULAR RESPONSE: IMPLICATIONS IN BONE REGENERATION

1 citations , August 2014 in “OhioLink ETD Center (Ohio Library and Information Network)”

Alkylated keratin from human hair can help deliver growth factors for bone healing.

research Genomic Characterization of the Human Type I Cuticular Hair Keratin hHa2 and Identification of an Adjacent Novel Type I Hair Keratin Gene hHa5

33 citations , October 1996 in “Journal of Investigative Dermatology”

research [Analysis of normal human hair keratins by two-dimensional polyacrylamide gel electrophoresis].

May 1988 in “PubMed”

research Fibre optic confocal imaging (FOCI) of keratinocytes, blood vessels and nerves in hairless mouse skin in vivo

36 citations , February 1998 in “Journal of Anatomy”

Fibre optic confocal imaging can visualize skin layers, blood vessels, and nerves in live mice.

research 519 Phase I/IIa clinical trial for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes

5 citations , April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

The gene therapy showed significant wound healing and was safe for treating severe RDEB.

research Epidermal E-Cadherin Dependent β-Catenin Pathway Is Phytochemical Inducible and Accelerates Anagen Hair Cycling

42 citations , July 2017 in “Molecular therapy”

A form of vitamin E promotes hair growth by activating a specific skin pathway.

research Type II Epithelial Keratin 6hf (K6hf) Is Expressed in the Companion Layer, Matrix, and Medulla in Anagen-Stage Hair Follicles

60 citations , December 2003 in “Journal of Investigative Dermatology”

K6hf is found in specific parts of hair follicles, nails, and tongue, and is linked to hair growth and structure.

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