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research Protein Kinase C Epsilon Signals Ultraviolet Light-induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism¶

28 citations , January 2005 in “Photochemistry and Photobiology”

Protein kinase C epsilon may increase skin cancer risk by affecting nearby cells.

Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Tissue Regeneration

research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration

August 2015 in “MOJ proteomics & bioinformatics”

ePUKs could be valuable for regenerative medicine due to their wound healing abilities.

research Mutation of the doublecortin gene in male patients with double cortex syndrome: Somatic mosaicism detected by hair root analysis

43 citations , September 2001 in “Annals of Neurology”

Hair root analysis can effectively detect somatic mosaicism in double cortex syndrome.

research Dermal Papilla Cells from Human Hair Follicles Express mRNA for Retinoic Acid Receptors in Culture

9 citations , December 1991 in “Annals of the New York Academy of Sciences”

research The Simplest Protocol for Rapid and Long-Term Culture of Primary Epidermal Keratinocytes from Human and Mouse

2 citations , January 2019 in “Methods in molecular biology”

A new method helps grow skin cells from humans and mice more easily and quickly.

Triad of Keratosis Pilaris, Ulerythema Ophryogenes, and 18p Monosomy: Zouboulis Syndrome

research Trias of keratosis pilaris, ulerythema ophryogenes and 18p monosomy: Zouboulis syndrome

15 citations , May 2014 in “Journal of dermatology”

Zouboulis syndrome is a rare condition that helps diagnose monosomy 18p early.

research Location,isolation and culture of epidermal stem cells of rats in vitro

January 2005 in “Journal of Shandong Univenity”

Epidermal stem cells are in hair follicle bulge regions, and isolation and culture methods are effective.

research Molecular Genetics of Keratinization Disorders – What’s New About Ichthyosis

18 citations , January 2020 in “Acta dermato-venereologica”

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

research 1340 Basal keratinocytes exhibit age-related epigenetic and transcriptomic alterations resulting in an altered metabolic profile

April 2023 in “Journal of Investigative Dermatology”

Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.

research Pili Trianguli et Canaliculi Is a Defect of Inner Root Sheath Keratinization

8 citations , May 2005 in “The American journal of dermatopathology/American journal of dermatopathology”

The hair defect is due to abnormal inner root sheath keratinization.

research How a Bird Gets Its Feathers: Insights from Chromatin Looping

3 citations , June 2020 in “Developmental Cell”

Feather patterns are influenced by enhancers and chromatin looping, and the structure of protein complexes important for hair growth has been detailed.

Human-Derived Immortalized Dermal Papilla Cells With Constant Expression of Androgen Receptor

research Human Derived Immortalized Dermal Papilla Cells With a Constant Expression of Testosterone Receptor

8 citations , March 2020 in “Frontiers in Cell and Developmental Biology”

Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.

research In vitro analyses of CD4-protein function in dedifferentiated keratinocyte cell lines

January 2023

The CD4 protein may play a role in the behavior of certain skin cells, affecting their growth, movement, and differentiation.

research 575 Senescent atrophic epidermis retains Lrig1+ stem cells and loses Wnt signaling, a phenotype shared with CD44KO mice

2 citations , August 2016 in “Journal of Investigative Dermatology”

research Atrichia with papular lesions resulting from a novel insertion mutation in the human hairless gene

19 citations , May 2006 in “Clinical and Experimental Dermatology”

Researchers found a new mutation causing total hair loss from birth.

research Peer Review #2 of "A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ (v0.1)"

February 2013

Activating CB1 can reduce keratin levels, potentially helping manage psoriasis and aid wound healing.

Differential Distribution of the Epigenetic Marker 5-Hydroxymethylcytosine in Hair Follicle Stem Cells During Bulge Activation

research Differential distribution of the epigenetic marker 5‐hydroxymethylcytosine occurs in hair follicle stem cells during bulge activation

4 citations , February 2019 in “Journal of Cutaneous Pathology”

The marker 5-hmC changes in hair follicle stem cells when they start to grow.

research Hair sheath keratins in follicular tumors. (5). Identification of hair sheath keratins in keratoacanthoma; Histopathological hair sheath structures in the tumor and their significance as differential histopathological criteria from squamous cell carcinoma.

January 1990 in “The Nishinihon Journal of Dermatology”

Follicular structures help differentiate keratoacanthoma from squamous cell carcinoma.

research P7 p63, K14 and p53 expression in epithelial layers of tumor-distant oral mucosa in patients with oral squamous cell carcinoma

March 2010 in “European Journal of Cancer Supplements”

research 454 Modeling epidermolysis bullosa simplex with cardiomyopathy using KLHL24-mutant pluripotent stem cells.

November 2025 in “Journal of Investigative Dermatology”

KLHL24-mutant stem cells help understand skin and heart disease.

research LncRNA RP11-818O24.3 promotes hair-follicle recovery via FGF2-PI3K/Akt signal pathway

4 citations , May 2024 in “Cytotechnology”

research HAIR KERATINIZATION IN HEALTH AND DISEASE

22 citations , October 1996 in “Dermatologic clinics”

Understanding intermediate filaments helps explain hair health and related diseases.

Small T Antigen From a Folliculotropic Polyomavirus Activates Canonical Wnt/β-Catenin Signaling In Vivo

research Type II Epithelial Keratin 6hf (K6hf) Is Expressed in the Companion Layer, Matrix, and Medulla in Anagen-Stage Hair Follicles

60 citations , December 2003 in “Journal of Investigative Dermatology”

K6hf is found in specific parts of hair follicles, nails, and tongue, and is linked to hair growth and structure.

research VAGINAL KERATINIZATION *IN VITRO**

13 citations , November 1959 in “Annals of the New York Academy of Sciences”

research Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice

81 citations , February 2014 in “EMBO molecular medicine”

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

research The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles

51 citations , January 2004 in “European Journal of Cell Biology”

Human cathepsin V can replace mouse cathepsin L to maintain normal skin and hair in mice.

research Correlation analysis of four KRTAP gene polymorphisms and cashmere fiber diameters in two cashmere goat breeds

September 2022 in “Canadian journal of animal science”

Certain gene variations are linked to the thickness of cashmere goat hair.

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