April 2017 in “Journal of Investigative Dermatology” The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.
13 citations
,
October 2010 in “Methods in molecular biology” Hair follicle culture helps study cell interactions and effects of substances on tissue growth.
49 citations
,
July 2006 in “British Journal of Dermatology” Calcifying epithelioma cells can differentiate into hair cortex and outer root sheath.
1 citations
,
January 2009 in “Journal of Dermatology and Venereology” Cells from the upper hair follicle grow more actively, suggesting stem cells may be located there.
759 citations
,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
June 2023 in “British Journal of Dermatology” Coinheritance of BRCA2 and CYLD genes may lead to new treatment options for certain cancers.
CCC1 is essential for ion balance and proper plant cell function.
19 citations
,
December 1990 in “Journal of Histochemistry & Cytochemistry” Foreskin keratinocytes and SVK14 cells express certain cytochrome P450 enzymes, unlike hair follicle keratinocytes.
March 2018 in “Journal of Experimental Biology” Hair curliness is caused by the arrangement and length of two different cell types.
January 2025 in “Cell Communication and Signaling” CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
January 2019 in “Institutional Repositories DataBase (IRDB)” Hair follicles and skin structures were successfully regenerated in the lab using specific cell arrangements and mechanical conditions.
61 citations
,
December 2016 in “The EMBO Journal” The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
14 citations
,
November 1979 in “Pediatric Research” 56 citations
,
January 1970 in “Cell and Tissue Research” September 1989 in “PubMed” The method allows detailed observation of hair tissue structures.
394 citations
,
October 2013 in “Nature” 50 citations
,
March 2001 in “Clinics in dermatology” Human hair is complex and grows in cycles starting from embryonic life.
5 citations
,
September 2012 in “Journal of Investigative Dermatology” Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.
55 citations
,
March 2014 in “EMBO Reports” Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
3 citations
,
May 2021 in “Genetics and Biodiversity Journal” Citrullus colocynthis fruit extract has strong antioxidant and cancer-fighting potential.
January 1994 in “Medical Entomology and Zoology” Electron microscopy helps understand skin structure and diseases.
13 citations
,
February 2020 in “Cold Spring Harbor Perspectives in Biology” New methods have helped find cells that create other cells in the body.
January 2003 in “Linchuang pifuke zazhi” Melanin granules can be expelled by exocytosis.
43 citations
,
October 2013 in “Journal of Investigative Dermatology” Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.
88 citations
,
January 1981 in “British Journal of Dermatology” A new method helps grow human hair cells using a cow eye lens.
17 citations
,
December 2014 in “Cell Stem Cell” Intravital imaging helps us better understand stem cells in their natural environment and could improve knowledge of organ regeneration and cancer development.
1 citations
,
October 2022 in “Veterinary pathology” Some canine hair follicle tumors contain amyloid deposits, with a protein called CK5 involved in their formation.
70 citations
,
April 2020 in “Journal of Molecular Cell Biology” Organoid technology helps create mini-organs for studying diseases and testing drugs.
August 1989 in “Proceedings ... annual meeting, Electron Microscopy Society of America/Proceedings, annual meeting, Electron Microscopy Society of America” The research provided a detailed view of the non-keratinous parts of human hair fibers.
24 citations
,
March 2022 in “Genome biology” scINSIGHT accurately identifies cell clusters and gene patterns in complex data.