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Identification of a Cyclosporine-Specific P450 Hydroxylase Gene Through Targeted Cytochrome P450 Complement Disruption in Sebekia Benihana

research Identification of a Cyclosporine-Specific P450 Hydroxylase Gene through Targeted Cytochrome P450 Complement (CYPome) Disruption in Sebekia benihana

13 citations , January 2013 in “Applied and Environmental Microbiology”

A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.

Effect of N-Acetylcysteine on Hair Follicle Changes in Mouse Model of Cyclophosphamide-Induced Alopecia: Histological and Biochemical Study

research Effect of N-acetylcysteine on hair follicle changes in mouse model of cyclophosphamide-induced alopecia: histological and biochemical study

April 2024 in “Histochemistry and cell biology”

N-acetylcysteine may prevent hair loss caused by chemotherapy.

research Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis

54 citations , February 2002 in “Carcinogenesis”

Increasing SSAT makes skin more prone to cancer.

research Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss.

26 citations , June 2003 in “PubMed”

Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

research 085 Coordinate expressions of cyclin-dependent kinase inhibitors and high sulfur protein in human hair follicles

June 1996 in “Journal of Dermatological Science”

research Coordinated inhibition of SOX9 and cell cycle progression by microRNA-200 restricts sebaceous gland fate specification

1 citations , January 2026

MicroRNA-200 prevents sebaceous gland development by inhibiting SOX9 and cell cycle progression.

research Mitochondrial DNA 10158T>C mutation in a patient with mitochondrial encephalomyopathy with lactic acidosis, and stroke-like episodes syndrome

5 citations , June 2020 in “Medicine”

A patient with a rare disease had a unique genetic mutation linked to their symptoms.

research Interleukin-1β-Induced Inhibition of Hair Growth In Vitro Is Mediated by Cyclic AMP

33 citations , January 1997 in “Journal of Investigative Dermatology”

research Spermidine/spermine-N¹-acetyltransferase: a key metabolic regulator

305 citations , March 2008 in “AJP Endocrinology and Metabolism”

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

research A new tool for conditional gene manipulation in a subset of keratin‐expressing epithelia

4 citations , July 2012 in “Genesis”

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.

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