January 2022 in “Stem cell biology and regenerative medicine” Dermal sheath cells can help grow new hair follicles and show promise in treating hair loss.
17 citations
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June 2018 in “Frontiers in Physiology” ADM scaffolds help skin heal by promoting a healing-type immune response.
Epidermal stem cells help renew skin and heal wounds, influenced by specific proteins and markers.
7 citations
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January 2022 in “Biomedicines” Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.
Combining regenerative therapy with light treatment can effectively promote hair growth.
1 citations
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November 2020 in “Biochemical Society transactions” Different types of skin stem cells can change and adapt, which is important for developing new treatments.
Conditioned media from dental pulp stem cells effectively stimulates hair growth.
November 2025 in “Trends in Immunotherapy” Exosomes from certain cells can improve hair regrowth by changing the immune response.
April 2026 in “Microsystems & Nanoengineering” HA-gel-dex hydrogels help heal wounds and regenerate tissue effectively.
5 citations
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December 2017 in “Tissue and cell/Tissue & cell” Researchers found stem cells in dog hair follicles using specific markers.
April 2024 in “Military Medical Research/Military medical research” Cellular and immunotherapies show promise for healing chronic wounds but need more research.
129 citations
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July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Scientists used a special imaging technique to observe that hair follicle regeneration involves cell division and structural changes, mostly in the lower part of the follicle, and that the dermal papilla at the base is crucial for regrowth.
May 2026 in “Stem Cell Research & Therapy” This study explores the use of exosomes derived from dental pulp mesenchymal stem cells (DPSC-Exos) as a novel treatment for androgenetic alopecia (AGA). Using a DHT-induced AGA mouse model, researchers found that DPSC-Exos significantly promoted hair regrowth, increased hair follicle density, and enhanced dermal thickness, showing efficacy comparable to minoxidil. The study identified that DPSC-Exos activate the PI3K/Akt signaling pathway, upregulating VEGFA and reconstructing the perifollicular vascular network. In vitro experiments demonstrated that DPSC-Exos counteracted DHT-induced suppression of dermal papilla cell functions, mediated by pro-angiogenic factors, and these effects were nullified by PI3K inhibition. The findings suggest that DPSC-Exos could be a promising, cell-free therapeutic strategy for AGA, with a clear mechanistic basis for future development.
165 citations
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June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
Tiny particles called extracellular vesicles show potential for improving skin health in cosmetics, but more research is needed to confirm their safety and effectiveness.
May 2024 in “International journal of molecular sciences” Platelet-derived products help regenerate tissue and are used in various skin and hair treatments.
2 citations
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March 2021 in “Journal of Cosmetic Dermatology” Umbilical cord-derived media is safe and effective for hair growth.
4 citations
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February 2024 in “Dermatology and Therapy” The procedure effectively improves the appearance of stretch marks in women.
April 2025 in “Frontiers in Bioengineering and Biotechnology” Gel-SHP helps skin heal faster.
1 citations
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August 2021 Biomimetic dermal papilla spheres can help regenerate hair to some extent.
49 citations
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March 2014 in “Journal of Investigative Dermatology” Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.
Exosomes from umbilical cord stem cells help hair growth.
3 citations
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April 2022 in “Veterinary world/Veterinary World” The mesenchymal stem cell-conditioned medium gel improved burn healing and hair growth in rats better than other treatments.
February 2026 in “Journal of Regenerative Medicine and Biology Research” Exosomes show promise for anti-aging and regenerative treatments.
1 citations
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January 2020 in “Aesthetic Surgery Journal” Platelet-rich plasma and stem cell therapies are accepted treatments for hair restoration, with specific protocols recommended for best results, but more standardization is needed in stem cell use.
1 citations
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August 2018 in “Journal of Investigative Dermatology” Muse cells keep their special features and can become different cell types even after being frozen and thawed three times.
20 citations
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March 2014 in “PubMed” Hair follicle stem cell research has advanced in understanding and using these cells for hair growth and skin repair.
78 citations
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June 2013 in “Science” Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.
December 2023 in “Journal of Food Science and Nutrition” Rosehip Seed Oil may help hair grow by activating important growth pathways and increasing hair follicle size in mice.