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Resident T Cell Activation Leads to Human Hair Follicle Immune Privilege Loss Ex Vivo, Which Is Prevented by the DHODH Inhibitor Farudodstat: Relevance for Alopecia Areata

research Resident T cell activation leads to human hair follicle immune privilege loss ex vivo, which is prevented by the DHODH inhibitor farudodstat: relevance for alopecia areata

April 2026 in “Frontiers in Medicine”

Farudodstat may help prevent hair loss in alopecia areata by stopping immune attacks on hair follicles.

research Efficacy and safety of deuruxolitinib, an oral selective Janus kinase 1/2 inhibitor, in adults with alopecia areata: Results from the THRIVE-AA2 Phase 3, randomized, double-blind, controlled trial

2 citations , November 2025 in “Journal of the American Academy of Dermatology”

Deuruxolitinib effectively regrows hair in adults with alopecia areata and is well tolerated.

research Impairment of Hair-Inducing Capacity of Three-Dimensionally Cultured Human Dermal Papilla Cells by the Ablation of STAT5

1 citations , January 2019 in “Annals of dermatology/Annals of Dermatology”

STAT5 is crucial for hair growth in 3D cultured human dermal papilla cells.

Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery

research Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery

11 citations , May 2010 in “Journal of Medicinal Chemistry”

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

research Loss of Gata6 causes dilation of the hair follicle canal and sebaceous duct

16 citations , July 2018 in “Experimental Dermatology”

Removing Gata6 causes hair follicle and sebaceous duct enlargement.

research Engineering MMP9-Responsive Antioxidative Micelle-Hydrogel Dressings for Sequential Inflammatory Remodeling and Pro-Angiogenesis in Diabetic Wound Healing

June 2026 in “Precision medicine and engineering.”

The hydrogel dressing RD@PVA helps heal diabetic wounds by reducing stress and improving blood vessel growth.

research Cutaneous adverse effects of BRAF inhibitors in metastatic malignant melanoma, a prospective study in 20 patients.

31 citations , March 2014 in “Journal of the European Academy of Dermatology and Venereology”

BRAF inhibitors for melanoma often cause skin side effects, but they can be managed with proper care.

research Murine skin-derived multipotent papillary dermal fibroblast progenitors show germline potential in vitro

4 citations , February 2023 in “Stem Cell Research & Therapy”

Mouse skin cells can become sperm-like cells in the lab.

research 6-Gingerol Inhibits Hair Shaft Growth in Cultured Human Hair Follicles and Modulates Hair Growth in Mice

17 citations , February 2013 in “PLOS ONE”

6-Gingerol, found in ginger, may slow down hair growth and could be used for hair removal.

Skin Barrier, Phenotypic and Genotypic Characterization of Autosomal Recessive Ichthyosis in TGM1-Deficient Jack Russell Terriers and Response to Topical Ceramide

research Skin barrier, phenotypic and genotypic characterisation of autosomal recessive ichthyosis in TGM1‐deficient Jack Russell Terriers and response to topical ceramide

August 2024 in “Veterinary Dermatology”

Topical ceramide treatment partially improves the skin condition in Jack Russell Terriers with a genetic skin disorder.

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