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510-540 / 1000+ resultsresearch (719) Signal Detection of Depression and Suicidality With the 5-Alpha Reductase Inhibitors: Evidence from the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) Database
The study analyzed the FDA Adverse Event Reporting System (FAERS) database to investigate psychiatric adverse drug reactions (ADRs) associated with 5-alpha reductase inhibitors (5-ARIs), specifically finasteride and dutasteride. A total of 27,578 ADRs were reported for finasteride, with 29.3% being psychiatric, while dutasteride had 9,161 ADRs with 13.3% psychiatric. Finasteride showed a higher disproportional reporting of psychiatric ADRs compared to dutasteride, with common issues including depressive disorders, anxiety, suicidality, and libido disorders. Despite the findings, a causal relationship between these psychiatric issues and 5-ARIs cannot be conclusively determined, highlighting the need for ongoing surveillance and further studies to clarify their neuropsychiatric safety profile.
research Frontotemporal dementia with parkinsonism presenting as posterior cortical atrophy
A woman's unique dementia was misdiagnosed, a genetic mutation increases Parkinson's risk with age, and finasteride may help with Tourette syndrome.
research Selection of Anti-Depressants in Geriatric Dermatoses- A Questionnaire Study of Dermatologists in Western Rajasthan, India
Most dermatologists in Western Rajasthan prefer the anti-depressant Doxepin for elderly skin conditions and often refer patients to a psychiatrist.
research 112 Post-Finasteride Syndrome – Outcomes of FDA Database
research Familial Cortisol Resistance: Differential Diagnostic and Therapeutic Aspects
The woman had a genetic condition causing high cortisol and androgen levels, treatable with dexamethasone.
research ALA-PDT in the Treatment of Diseases of Hair Follicles and Sebaceous Glands
research Early Diagnosis and Treatment of Discoid Lupus Erythematosus
Early diagnosis and treatment of discoid lupus erythematosus improve outcomes.
research Pericardial, pleural effusion and anasarca: A rare complication of low-dose oral minoxidil for hair loss
A woman developed swelling in her body after taking low-dose oral minoxidil for hair loss, but it resolved after stopping the medication.
research Disposition and metabolism of finasteride in dogs.
research Prescribers alerted to potential adverse effects of finasteride and montelukast
research Frequency of Different Dermatosis Presented at OPD in Sir Syed Hospital Qayoomabad
Young women were the most common patients at the dermatology clinic.
research Reconnecting
The DNA convention was a valuable opportunity for learning and networking, especially after COVID-19.
research DP10 Scalp disease in dermatomyositis
Scalp disease in dermatomyositis causes significant symptoms and has unique features.
research 54553 Diversity in dermatology datasets: what next?
Dermatology datasets need more diversity in skin tones and ethnic representation.
research Monthly versus quarterly dutasteride mesotherapy for male androgenetic alopecia: A randomized trial
research Case report: Dermatosis neglecta mimicking pemphigus foliaceus in association with obsessive–compulsive disorder
Proper cleansing can resolve dermatosis neglecta, which may indicate underlying psychiatric issues.
research Enzalutamide/finasteride/goserelin/zoledronic-acid
research Finasteride and floppy iris syndrome: What role can the dermatologist play?
research FRI334 A Case Of Delayed Onset Sheehan's Syndrome With Diabetes Insipidus
A woman was diagnosed with Sheehan's syndrome and a rare complication of diabetes insipidus 33 years after symptoms began, improving with hormone therapy.
research Dovobet ointment under occlusion overnight for troublesome scalp psoriasis
Dovobet ointment used overnight effectively reduces scalp psoriasis severity and itch.
research Association of 5-α reductase inhibitors and sexual dysfunction: A RADAR report
Using hair loss drugs finasteride and dutasteride may cause sexual side effects.
research EDA Missense Variant in a Cat with X-Linked Hypohidrotic Ectodermal Dysplasia
A genetic mutation in the EDA gene causes hypohidrotic ectodermal dysplasia in cats.
research Mast cell hyperplasia in the skin of Dsg4-deficient hypotrichosis mice, which are long-living mutants of lupus-prone mice
A gene mutation in mice causes increased mast cells and disorganized hair follicles in their skin.
research The Antiandrogens
research Use of Videodermatoscopy in Scalp Disorders
research Appropriateness of oral drugs for long-term treatment of lower urinary tract symptoms in older persons: results of a systematic literature review and international consensus validation process (LUTS-FORTA 2014)
Dutasteride, fesoterodine, and finasteride are beneficial for older patients, while most other drugs should be used cautiously or avoided.
research 10.1063/5.0132123.1
research PD49-02 MEDICATIONS MOST COMMONLY ASSOCIATED WITH ERECTILE DYSFUNCTION: EVALUATION OF THE FOOD AND DRUG ADMINISTRATION NATIONAL PHARMACOVIGILANCE DATABASE
Certain medications, especially 5-alpha reductase inhibitors, are commonly linked to erectile dysfunction.
research Plain Language Summaries
Most clinicians follow discharge guidelines, many lupus patients don't use sunscreen regularly, dithranol is effective for psoriasis, biopsy methods should be based on lesion type, voriconazole may raise skin cancer risk, a new scale can help diagnose female hair loss early, and most melanomas may develop from existing moles.