research Organoid technology for tissue engineering
Organoid technology helps create mini-organs for studying diseases and testing drugs.
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180-210 / 1000+ resultsresearch Organoid‐Guided Precision Medicine: From Bench to Bedside
Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
research Genetic association of wool quality characteristics in United States Rambouillet sheep
Certain genetic markers linked to wool quality in Rambouillet sheep were identified, which can guide better breeding choices.
research Lgr6+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors
UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.
research Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages
Epidermal β-catenin activation changes the dermis by signaling different fibroblast types.
research Keratinocytes maintain compartmentalization between dermal papilla and fibroblasts in 3D heterotypic tri‐cultures
Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
research Incorporation of hair follicles in 3D bioprinted models of human skin
3D bioprinting can now create skin with hair-like structures for medical use.
research Fabrication of Chimeric Hair Follicles for Skin Tissue Engineering
Engineered skin with hair follicles can improve burn treatments.
research Development and Homeostasis of the Skin Epidermis
The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
research Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration
Wnt signaling helps regenerate hair follicles by affecting how skin cells sense and respond to mechanical forces.
research Genetic basis of skin appendage development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
research Stem cell quiescence acts as a tumour suppressor in squamous tumours
Inactive hair follicle stem cells help prevent skin cancer.
research Mudanças associadas ao envelhecimento capilar
Hair aging leads to color loss and reduced density, and dermatologists are key in treating it to improve quality of life.
research Bioadhesive Polydopamine-Vitamin A Derivative Hydrogels Reprogram the Wound Microenvironment for Scarless Wound Healing and Hair Follicle Regeneration
The hydrogel helps wounds heal without scars and promotes new hair growth.
research Dermal β-Catenin Is Required for Hedgehog-Driven Hair Follicle Neogenesis.
β-Catenin is essential for new hair growth after skin injury.
research Skin‐on‐a‐chip strategies for human hair follicle regeneration
New technologies show promise for better hair regeneration and treatments.
research 1410 Non-coding double stranded RNA induces retinoic acid synthesis and retinoid signaling to control regeneration
Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.
research Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis
Sox2-positive cells determine specific hair follicle types in mammals.
research OVO Homolog-Like 1, a Target Gene of the Wnt/β-Catenin Pathway, Controls Hair Follicle Neogenesis
The OVOL1 gene, controlled by β-catenin, is crucial for creating hair follicles.
research Stem Cell: Current and Future State
Stem cells show promise for hair loss treatment, but no effective product for hair regeneration has been developed yet.
research Regeneration of fat cells from myofibroblasts during wound healing
Some wound-healing cells can turn into fat cells around new hair growth in mice.
research Human Papillomavirus E6/E7 Oncogenes Promote Mouse Ear Regeneration by Increasing the Rate of Wound Re-epithelization and Epidermal Growth
HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.
research A model system to analyse the ability of human keratinocytes to form hair follicles
Scientists developed a system to study human hair growth using skin cells, which could help understand hair development and improve skin substitutes for medical use.
research Aberrant Wnt Signaling Induces Comedo-Like Changes in the Murine Upper Hair Follicle
Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.
research Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia
Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
research Fibroblast heterogeneity and tertiary lymphoid tissues in the kidney
Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
research Stem cell dynamics, migration and plasticity during wound healing
Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
research Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately
Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition
The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.