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research Hair Growth Defects in Insig-Deficient Mice Caused by Cholesterol Precursor Accumulation and Reversed by Simvastatin

46 citations , January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

research The roles of autophagy and apoptosis in burn wound progression in rats

45 citations , June 2013 in “Burns”

Treatments for burn wounds in rats should be timed according to whether autophagy or apoptosis is more active at certain times after the burn.

research Mitoxantrone

44 citations , August 1996 in “Drugs & Aging”

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

research Hypervitaminosis A

44 citations , September 1948 in “Radiology”

Too much vitamin A can cause serious health problems.

Proxalutamide Reduces the Rate of Hospitalization for COVID-19 Male Outpatients: A Randomized Double-Blinded Placebo-Controlled Trial

research Proxalutamide Reduces the Rate of Hospitalization for COVID-19 Male Outpatients: A Randomized Double-Blinded Placebo-Controlled Trial

42 citations , July 2021 in “Frontiers in Medicine”

Proxalutamide significantly lowered hospital admissions for male COVID-19 patients compared to a placebo.

research Hutchinson-Gilford Progeria Syndrome—Current Status and Prospects for Gene Therapy Treatment

39 citations , January 2019 in “Cells”

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Cyclophosphamide: As Bad as Its Reputation? Long-Term Single Centre Experience of Cyclophosphamide Side Effects in the Treatment of Systemic Autoimmune Diseases

research Cyclophosphamide: As bad as its reputation? Long-term single centre experience of cyclophosphamide side effects in the treatment of systemic autoimmune diseases

39 citations , October 2014 in “Schweizerische medizinische Wochenschrift”

Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.

research Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle

39 citations , May 2010 in “Stem Cells”

Ephrins slow down skin and hair follicle cell growth.

research Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes

35 citations , August 2010 in “The American journal of pathology”

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

research A novel mutation in the connexin 26 gene (GJB2) in a child with clinical and histological features of keratitis–ichthyosis–deafness (KID) syndrome

34 citations , September 2010 in “Clinical and Experimental Dermatology”

A new gene mutation linked to KID syndrome was found, expanding genetic knowledge.

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