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Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

The treatment improved hair growth and was well-received without side effects.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

5α-reductase inhibitors, like Finasteride and Dutasteride, help manage benign prostatic hyperplasia.

Abietic acid from pine resin can effectively inhibit testosterone 5α-reductase.

The new gel for hair loss is safe, effective, and reduces side effects.

Blocking certain brain processes reduces mating behavior in female rats.

Testosterone, DHT, and estradiol significantly affect hair cell growth.

Androgens can affect glucocorticoid signaling in specific mouse brain areas.

Antiandrogens can treat acne, hirsutism, and seborrhea by reducing sebum production and androgen action.

Girls have higher DHEA levels earlier in puberty than boys, indicating earlier development.

Human skin releases different steroids, with some coming from sebaceous glands and others from sweat glands.

Dutasteride more effective than finasteride for hair growth; SM04554 safe and potentially effective for hair loss.

Small injections of dutasteride improved hair thickness in men with hair loss without major side effects.

5alpha-DHP may be a safe, effective treatment for certain seizures without causing sedation.

3α‐OH‐DHP is essential for reducing nerve activity related to blood pressure control during pregnancy.

Most antiandrogen treatments effectively reduce acne in hyperandrogenic women, but finasteride is the least effective.

Higher SRD5A2 expression predicts better response to finasteride in treating urinary symptoms.

Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.

The treatment temporarily improved symptoms of hyperandrogenism in adolescents.

New compounds show promise as nonsteroidal treatments for hair loss.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

Clascoterone is a promising topical treatment for hair loss and acne with fewer side effects.