research Decoding Hyperpigmentation from Biological Mechanisms to Actives with Clinically Proven Topical Efficacy: A Narrative Review
Combining multiple ingredients is the most effective treatment for hyperpigmentation.
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research Clinical and Dermoscopic Evaluation of the Efficacy Melasma Treatment with Oral Tranexamic Acid
Oral tranexamic acid is a safe and effective treatment for melasma.
research Laser Depigmentation in Extensive Vitiligo
research Melasma, a photoaging disorder
Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.
research Can hair be protected from oxidative damage during and after bleaching
L-arginine, hydrolysed keratin, and cystine-silanol copolymer can help protect hair from damage during and after bleaching.
research Platelet-Rich Plasma in Melasma—A Systematic Review
Platelet-rich plasma (PRP) can significantly improve melasma, a skin pigmentation disorder, but may not add benefits when used with certain other treatments.
research Alkylating Agents
Alkylating agents can kill cancer cells but may cause skin and allergic reactions.
research 한방복합처방단의 발모효과 및 멜라닌 생성 촉진효과
The modified oriental prescriptions help hair growth and melanin production without irritating the skin.
research Platelet‐rich plasma is a promising therapy for melasma
Platelet-rich plasma therapy could be an effective treatment for melasma with minimal side effects.
research Changing the shape of hair with keratin peptides
Keratin peptides can change hair shape gently without harsh chemicals.
research Carvone Decreases Melanin Content by Inhibiting Melanoma Cell Proliferation via the Cyclic Adenosine Monophosphate (cAMP) Pathway
Carvone helps treat skin issues by reducing melanin and stopping harmful cell growth.
research Silk Fibroin-Based Hydrogel Microneedles Deliver α-MSH to Promote Melanosome Delivery for Vitiligo Treatment
Silk fibroin microneedles can effectively treat vitiligo by promoting skin pigmentation.
research Melanocortins in fibroblast biology – current update and future perspective for dermatology
α-MSH may help treat skin inflammation and fibrosis.
research Epidermal cells: methods and protocols
research Major approaches of molecular and physiopathological mechanisms for hormonal treatment of melasma: a systematic review
Estrogens and progesterone are key in regulating melasma pigmentation.
research The antimycotic agent clotrimazole inhibits melanogenesis by accelerating ERK and PI3K-/Akt-mediated tyrosinase degradation
Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.
research Permanent Makeup (PMU) Removal with Plant Origin Extracts
Plant extracts can help remove permanent makeup without lasers.
research Abstracts: Reduction‐induced surface modification of human hair
Chemical treatments change hair surface properties, making it more hydrophilic and able to bind conditioners.
research The therapeutic use of topical contact sensitizers in benign dermatoses
Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.
research Structural Changes of Hair Keratin by Reduction, Heat and subsequent Oxidation Treatments
DTDG in hair treatments reduces damage and preserves hair structure.
research ??-Hydroxy Acid???Based Cosmetic Procedures
Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.
research N,N-Dimethylglycine Sodium Salt Exerts Marked Anti-Inflammatory Effects in Various Dermatitis Models and Activates Human Epidermal Keratinocytes by Increasing Proliferation, Migration, and Growth Factor Release
N,N-Dimethylglycine Sodium Salt helps reduce skin inflammation and improves skin cell growth and healing.
research Modern Dermabrasion Techniques: A Personal Appraisal
Improved dermabrasion techniques in 1987 led to better treatment results for skin issues like acne scars.
research Epidermal cell proliferation and modulation of the protective potency of dexamethasone against phorbol ester-induced ornithine decarboxylase activity
Dexamethasone reduces inflammation and delays skin cell changes caused by TPA.
research Regeneration of Mouse Skin Melanocyte Stem Cells In Vivo and In Vitro
The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.
research The Efficacy of Various Degreasing Agents Used in Trichloroacetic Acid Peels
Acetone is not more effective than other degreasers and is more flammable.
research In vitro Differentiation of Melanocyte Stem Cells Derived from Vitiligo Patients into Functional Melanocytes
Melanocyte stem cells from non-affected skin in vitiligo patients can become functional melanocytes for potential therapy.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research Application of Marine Microbial Natural Products in Cosmetics
Marine microbes could be used in cosmetics for sun protection, skin care, and possibly preventing hair loss.
research Repigmentation of Leukoderma by Minigrafts of Normally Pigmented, Autologous Skin
Transplanting small skin grafts can successfully repigment leukoderma.