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Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

Lipase H is important for hair follicle function and shaping hair fibers.

TSC2-/meth cells can cause skin lesions, hair growth, and lung issues, and may be treated with chromatin remodeling agents.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Inherited color dilution in rabbits is linked to DNA methylation changes.

Teak leaf extract contains compounds that could help treat hair loss.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

The protein DDX6 helps keep skin cells renewing properly by controlling the production of certain other proteins and breaking down those that cause cells to mature too quickly.

Equisetum debile extract may help with hair loss by inhibiting enzymes and reducing inflammation.

18-MEA is essential for hair's water resistance, and a conditioner with 18-MEA and SPDA can restore it.

Exosomal miR-222-3p reduces melanin production in rabbits by targeting the SOX10 gene.

5α-reductase enzyme affects hormone levels, influencing conditions like acne and hair loss.

A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

The models can help find better inhibitors for conditions like baldness and prostate disorders.

Desmoglein 3 is important for keeping hair follicle stem cells inactive and maintaining their special properties.

Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

New mutations in the DSG4 gene cause a rare hair condition.

Epristeride's metabolism involves key metabolites and proteins, affecting its use in doping tests.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

The method effectively measures drug impact on DHT levels in prostate treatments.

Targeting specific miRNAs may help treat hair follicle issues caused by hydrogen peroxide.

Glycyrrhizic acid may help reduce unwanted hair growth.

Neurosteroids may help metyrapone reduce cocaine addiction.

Changes in KRT17 gene activity linked to wool production in Angora rabbits.

Gsdma3 affects hair growth by controlling Wnt5a, which influences hair cell development.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.