115 citations
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November 2004 in “Brain Behavior and Immunity” Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.
112 citations
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November 2023 in “Nano-Micro Letters” Nanozymes show promise for effective and safe cancer treatment.
109 citations
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October 2007 in “American Journal of Human Genetics” Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.
96 citations
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September 2017 in “Analytica Chimica Acta” Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.
96 citations
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June 2017 in “Nature Communications” A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
96 citations
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April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
89 citations
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November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
89 citations
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October 1996 in “Dermatologic Clinics” Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
88 citations
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January 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.
86 citations
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May 2008 in “Cytokine & growth factor reviews” TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
85 citations
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August 2015 in “Journal of Applied Genetics” Mutations in specific genes disrupt development of sweat glands, teeth, hair, skin, and nails in HED.
82 citations
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February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
82 citations
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September 2011 in “Quality of Life Research” Choosing the right recall period for patient feedback is important for accurate data and depends on the disease, symptom changes, and patient impact.
82 citations
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April 1981 in “Clinical endocrinology” A girl with rickets and hair loss was found to have a rare condition where her body didn't respond to vitamin D treatment.
81 citations
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January 2011 in “European Journal of Internal Medicine” Despite progress, better treatments and understanding are needed for the high rates of long-term issues and deaths linked to eating disorders.
81 citations
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March 2009 in “Seminars in Cutaneous Medicine and Surgery” Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.
81 citations
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January 2003 in “The FASEB Journal” Follistatin helps hair growth and cycling, while activin prevents it.
77 citations
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August 2025 in “Signal Transduction and Targeted Therapy” Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
76 citations
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February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
75 citations
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September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
73 citations
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March 2014 in “Journal of The American Academy of Dermatology” Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.
72 citations
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January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
72 citations
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December 2009 in “Organic and Biomolecular Chemistry” Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.
72 citations
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April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
70 citations
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August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
70 citations
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May 2014 in “JAMA Dermatology” The representation of skin conditions in medical reviews partly matches their real-world impact.
65 citations
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October 2008 in “Journal of Neuroendocrinology”
64 citations
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December 2012 in “Stem Cell Reviews and Reports” Human hair follicle cells can be turned into stem cells similar to embryonic stem cells.
60 citations
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September 2016 in “Dermatologic Surgery” PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.
59 citations
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February 2021 in “BMJ” High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.