November 2021 in “CRC Press eBooks” Hair color is determined by melanin and can be affected by genetic conditions like albinism.
September 2019 in “Journal of Investigative Dermatology” PCE-DP brightens skin and promotes hair growth by enhancing cell growth and reducing melanin uptake.
28 citations
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December 2019 in “Skin appendage disorders” Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.
450 citations
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January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
2 citations
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May 2023 in “Photobiomodulation, photomedicine, and laser surgery” Light therapy is effective and safe for treating skin color disorders like vitiligo and dark spots.
Retinoids can help treat skin pigmentation disorders by affecting melanin production.
September 2017 in “Journal of Investigative Dermatology” Photodynamic therapy can potentially remove nonpigmented hair by damaging hair follicles.
May 2024 in “Pigment International” Several treatments are effective for pigmentary disorders like vitiligo and melasma.
April 1986 in “CRC Press eBooks” Hair color is determined by melanins produced in hair cells.
November 2021 in “Natural product research” Certain polyphenols may help treat skin pigmentation disorders.
September 2012 in “British Small Animal Veterinary Association eBooks” The document concludes that pigmentation disorders in animals involve complex interactions between melanocytes and keratinocytes.
6 citations
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October 2006 Understanding repigmentation mechanisms in vitiligo can improve treatments and patient outcomes.
119 citations
,
May 1987 in “The Journal of Dermatologic Surgery and Oncology” Most patients' skin darkening after sclerotherapy fades on its own within 6-24 months.
March 2026 in “European Journal of Biomedical and Life Sciences” Restorative dermopigmentation improves skin appearance and function by addressing specific skin issues.
81 citations
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October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain genes control the color of human hair by affecting pigment production.
37 citations
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October 2017 in “Advanced drug delivery reviews” The review suggests that there are various treatments to help restore skin color after severe burns.
59 citations
,
March 2003 in “The Lancet” Imatinib can repigment grey hair, while SU11428 can cause temporary hair depigmentation.
November 2023 in “Journal of the American Academy of Dermatology” Skin of color can spontaneously repigment after a phenol-croton oil chemical peel.
2 citations
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September 2023 in “PubMed” Laser-assisted prostaglandin analogs improve hypopigmented scars safely, but more research is needed.
1 citations
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May 2017 in “Journal of Stem Cell Research & Therapeutics” Pluripotent stem cells show promise for treating skin color loss disorders like vitiligo.
9 citations
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July 2012 in “Dermatitis” Hair dye with para-phenylenediamine can cause skin depigmentation.
February 2005 in “CRC Press eBooks” Hair color is due to active pigment cells in hair during growth.
1 citations
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August 2018 in “Dermatologic Surgery”
1 citations
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July 2015 in “British Journal of Dermatology” Imiquimod improved skin pigmentation in most patients with xeroderma pigmentosum and may prevent further skin cancer, but some treatments can have side effects.
November 2022 in “Skin Appendage Disorders” PT-20 did not significantly improve gray hair repigmentation.
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
Melanocyte transplantation can safely restore skin color, especially in stable vitiligo, but must be chosen carefully based on the disease phase.
November 2025 in “International Journal of Advanced Research” Platelet-rich plasma therapy effectively treated laser-induced skin lightening.
7 citations
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December 1981 in “International Journal of Dermatology” Understanding genes can help diagnose and treat skin color disorders.
January 2025 in “Archives of Dermatological Research”