September 2012 in “PharmacoEconomics & Outcomes News” Finasteride doesn't harm quality of life.
76 citations
,
December 1997 in “Fertility and Sterility” Finasteride reduces hair growth better, but spironolactone has more side effects.
October 2024 in “Journal of the Endocrine Society” Estrogen alone may effectively suppress testosterone in some transfeminine individuals.
January 2015 in “Turkiye Klinikleri Journal of Endocrinology” PCOS patients with autoimmune thyroid disease have lower DHEAS levels.
22 citations
,
March 2003 in “Steroids” PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.
April 2021 in “Reactions Weekly” Finasteride increases risk of depression, possibly suicidal thoughts, and sexual dysfunction.
September 2019 in “Reactions Weekly” Man experienced post-finasteride syndrome symptoms after using finasteride and dutasteride for hair loss.
10 citations
,
November 2019 in “Neuroendocrinology” Measuring 17-hydroxyprogesterone in hair can help monitor androgen levels in people with congenital adrenal hyperplasia.
Testosterone pellets may help women's sexual function but have safety concerns and need more research.
January 2025 in “HORMONES” Gender-affirming hormone treatments need better patient-focused outcome measurements and standardized data collection.
May 2024 in “Reactions weekly”
33 citations
,
October 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces hair growth and is safe for women with excessive hair.
33 citations
,
December 2015 in “Neuroendocrinology” Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.
1 citations
,
March 2012 in “Journal of Dermatological Science” Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
April 2016 in “Journal of The American Academy of Dermatology” Dutasteride works better than finasteride for hair growth with similar side effects.
October 2004 in “Australian Prescriber” Lifestyle changes are more effective than medication for reducing type 2 diabetes risk.
43 citations
,
December 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Progesterone protects neurons from damage by converting to allopregnanolone, which works through GABAA receptors.
68 citations
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January 2022 in “International Journal of Molecular Sciences” PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
April 2008 in “Sexologies” Knowing about potential side effects can make them more likely to happen.
April 1992 in “Current opinion in therapeutic patents” New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.
50 citations
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March 2011 in “European Journal of Endocrinology” Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.
October 2024 in “Journal of the Endocrine Society” Estrogen alone can lower testosterone in some transfeminine people.
55 citations
,
July 2013 in “Dermatologic therapy” Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.
86 citations
,
July 1993 in “Drugs” Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
The treatment changed hormone levels and increased sexual behavior in female capuchin monkeys.
47 citations
,
January 2016 in “Brain Behavior and Immunity” 5α-reduced progestogens may reduce mood issues and brain damage linked to HIV-1 Tat.
30 citations
,
July 2001 in “BJUI” Combination therapy improves urinary flow and reduces residual urine, but needs better stent design.
2 citations
,
April 2020 in “Clinical and experimental obstetrics & gynecology” Hair levels of estradiol and progesterone are higher in premenopausal than postmenopausal women, but the difference isn't statistically significant, indicating the need for a better measurement method.
May 2021 in “Journal of the Endocrine Society” A woman developed male characteristics after using unregulated hormone therapy.
11 citations
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August 2000 in “Journal of Endocrinology” DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.