126 citations
,
January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
116 citations
,
September 2001 in “Journal of The American Academy of Dermatology” Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.
108 citations
,
January 2003 in “Journal of Cosmetic Dermatology” Wrinkles form due to structural skin changes and vary in type and treatment response.
95 citations
,
July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
88 citations
,
December 2018 in “Advanced Healthcare Materials” Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.
83 citations
,
January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
81 citations
,
September 2005 in “The American journal of pathology” Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
79 citations
,
January 2015 in “Journal of Materials Chemistry B” Smart biomaterials that guide tissue repair are key for future medical treatments.
73 citations
,
July 2016 in “Cosmetics” Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.
72 citations
,
December 1996 in “Journal of Investigative Dermatology” Human hair follicles can regenerate after removal, but with low success rate.
71 citations
,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” HFMs can help study hair growth and test potential hair growth drugs.
66 citations
,
December 2014 in “Nature Communications” Fibroblasts can be turned into melanocytes for potential skin treatments.
65 citations
,
April 2020 in “International Journal of Molecular Sciences” PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
57 citations
,
February 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
57 citations
,
March 2011 in “The American Journal of Dermatopathology” Chemotherapy can cause permanent, non-reversible hair loss similar to pattern baldness.
55 citations
,
April 2018 in “Advanced Healthcare Materials” Hydrogels could lead to better treatments for wound healing without scars.
55 citations
,
October 2009 in “Clinics in Plastic Surgery” Burn reconstruction improves with new techniques, materials, and tissue engineering.
49 citations
,
January 2018 in “Theranostics” The new skin patch with human matrix and antibiotic improves wound healing.
41 citations
,
September 2010 in “Journal of dermatological science” Bone marrow and umbilical cord stem cells can help grow new hair.
40 citations
,
March 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.
36 citations
,
May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
31 citations
,
September 2016 in “PLoS ONE” Cell division orientation varies by body site and is linked to epidermal thickness and cell density.
30 citations
,
May 2018 in “Experimental Dermatology” The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
29 citations
,
December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.
27 citations
,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
27 citations
,
March 2018 in “Biomaterials” Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
23 citations
,
September 2020 in “Journal of Cosmetic Dermatology” Injectable Platelet-Rich Fibrin (I-PRF) showed positive results for treating hair loss, skin texture, wrinkles, and wounds.
23 citations
,
September 2015 in “PLOS ONE” Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.
23 citations
,
January 2014 in “Molecular Therapy” Applying a special DNA plasmid to the skin can make it thicker and stronger.
22 citations
,
August 2017 in “Stem cells and cloning” Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.