July 2025 in “Journal of Investigative Dermatology” Hhip-Cre effectively targets dermal papilla cells for gene manipulation in hair biology.
42 citations
,
April 2016 in “Plastic and reconstructive surgery/PSEF CD journals” The hydrogel with fractionated PRP improves skin regeneration by enhancing wound healing and growth of skin structures.
19 citations
,
May 2020 in “Cells” Substance from human umbilical cord blood cells promotes hair growth.
8 citations
,
February 2017 in “International journal of molecular sciences” Mollusc egg extract helps skin and hair cells grow and heal.
1 citations
,
June 2021 in “Journal of pharmacopuncture” CBD may help restore hair growth-related protein levels in alopecia caused by hormones or other factors.
May 2024 in “The journal of investigative dermatology/Journal of investigative dermatology” β-Catenin is essential for new hair growth after skin injury.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
January 2022 in “Stem cell biology and regenerative medicine” Improving dermal papilla cells can help regenerate hair follicles.
759 citations
,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
479 citations
,
January 2005 in “BioEssays” Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
338 citations
,
July 2009 in “Development” Sox2-positive cells determine specific hair follicle types in mammals.
277 citations
,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
231 citations
,
December 1999 in “Journal of Investigative Dermatology” Hair follicle size is mainly influenced by the number of cells and extracellular matrix volume, with cell number having a larger impact.
225 citations
,
April 2018 in “Journal of Investigative Dermatology” Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
223 citations
,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
219 citations
,
July 1995 in “PubMed” Keratinocyte growth factor promotes hair growth and reduces hair loss from chemotherapy.
211 citations
,
May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
205 citations
,
April 2005 in “Journal of Investigative Dermatology” Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
159 citations
,
January 2006 in “BMC Cell Biology” Wnt signaling can improve skin healing by promoting epithelial growth.
132 citations
,
August 2008 in “Development” Dlx3 is essential for hair growth and regeneration.
126 citations
,
August 2018 in “Molecular Systems Biology” Fibroblast state switching is crucial for skin healing and development.
126 citations
,
January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
121 citations
,
March 1989 in “Journal of Investigative Dermatology” Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.
113 citations
,
July 2015 in “Journal of Cosmetic Dermatology” Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.
106 citations
,
October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
97 citations
,
March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
89 citations
,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
88 citations
,
May 2005 in “Journal of Dermatological Science” Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
87 citations
,
September 2016 in “Journal of Controlled Release” Nanoparticles can improve drug delivery to hair follicles but struggle to penetrate deeper skin layers.