67 citations
,
February 1994 in “Developmental dynamics” Specific proteins and molecules play key roles in the development of human hair follicles.
53 citations
,
September 2013 in “Journal of Investigative Dermatology” Hair follicle cells help protect against immune attacks by regulating T-cell activity.
49 citations
,
September 2007 in “Journal of Investigative Dermatology” The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.
46 citations
,
November 1998 in “Experimental Cell Research” K15 gene is mainly active in the basal layers of hair follicles and epithelia, aiding early skin cell development.
35 citations
,
November 2020 in “Experimental Dermatology” Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.
14 citations
,
October 2019 in “Journal of Cellular Physiology” Micrografts promote hair growth in androgenetic alopecia treatment.
13 citations
,
December 1983 in “Canadian journal of zoology” Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.
1 citations
,
March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
1 citations
,
November 2020 in “Research Square (Research Square)” The study found specific skin cells and genes that may affect the quality of cashmere in Liaoning Cashmere Goats.
1 citations
,
September 2004 in “Experimental Dermatology” MC-1R is present in skin cells and may help reduce inflammation.
March 2026 in “Journal of Bioscience and Bioengineering” Oxytocin from hair cells helps hair growth and stem cell increase.
March 2025 in “Medical & Clinical Research” Stem cell therapy can help regrow hair and increase hair density.
January 2025 in “International Journal of Pharma Medicine and Biological Sciences” DP cells interact with immune cells, possibly causing hair loss in Alopecia Areata.
November 2024 in “Journal of Investigative Dermatology” Adrenomedullin 2 stops cell growth and causes cell death in human hair follicles.
April 2023 in “Journal of Investigative Dermatology” The study found that aging hair follicle stem cells change behavior, leading to hair loss, but drugs targeting these cells may help restore hair growth.
April 2023 in “Journal of Investigative Dermatology” The research mapped gene activity in developing mouse skin and found key markers for skin cell types and changes from fetal to early postnatal stages.
August 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” Stem cell therapies show potential for treating hair loss with fewer side effects.
April 2017 in “Journal of Investigative Dermatology” The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.
The estrogen receptor pathway controls hair growth cycles and affects skin cell growth.
151 citations
,
February 2006 in “Stem Cells and Development” Hair follicles can be a good source of stem cells like those from bone marrow.
95 citations
,
July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
80 citations
,
June 2008 in “Biomaterials” EVAL membranes help create cell structures that can regrow hair follicles.
47 citations
,
December 2003 in “Journal of Investigative Dermatology” DS cells in hair follicles can help form and restore hair, especially in hair loss conditions.
46 citations
,
September 2014 in “Tissue engineering. Part A” Researchers created hair-inducing human cell clusters using a 3D culture method.
35 citations
,
January 2014 in “Journal of Tissue Engineering” Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
20 citations
,
October 2008 in “Archives of dermatological research” Angiogenin helps hair grow by stimulating cell growth and blood vessel formation.
7 citations
,
July 2019 in “International Journal of Molecular Sciences” PGA-4HGF may help treat hair loss by activating hair growth pathways and extending the hair growth phase.
6 citations
,
February 2023 in “Genes” CUX1 boosts sheep hair cell growth and affects curl patterns.
5 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” The "Two-Cell Assemblage" assay is a new, simple method to identify substances that may promote hair growth.
1 citations
,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.