research The Role of Interface Geometry and Appendages on the Mesoscale Mechanics of the Skin
Skin's uneven surface and hair follicles affect its stress and strain but don't change its overall strength, and help prevent the skin from peeling apart.
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research Perspectives on Dermatopathology
Dermatopathology has made significant progress but many skin diseases remain incurable, requiring ongoing research.
research 877 Integration of magnetic tweezers and traction force microscopy for exploring the mechanobiology of keratinocyte cell-cell and cell-matrix anchoring junctions
The conclusion is that a new method combining magnetic tweezers and traction force microscopy may help understand skin cell interactions and diseases.
research TERMIS ‐ AMERICAS Toronto, Ontario, Canada July 10–13, 2022
Advancements in skin treatment and wound healing include promising gene therapy, 3D skin models, and potential new therapies.
research The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Immune-mediated alopecias and their mechanobiological aspects
research Vitamin D and the skin: Physiology and pathophysiology
Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
research Skin Development and Disease: A Molecular Perspective
Understanding molecular processes in skin development is key to creating targeted treatments for skin disorders.
research THE COMPARISON OF THE BIOPHYSICAL SKIN PARAMETERS AND HAIR GROWTH IN THE PATIENTS WITH ACNE TREATED WITH ISOTRETINOIN AND BIOTIN OR ONLY ISOTRETINOIN TREATMENT
research Cutaneous adverse effects of targeted therapies
Targeted cancer therapies often cause skin side effects, needing dermatologist care.
research Cytokine Therapy in Dermatology
Cytokine therapy is promising for treating skin conditions like vitiligo and psoriasis.
research DERMAL-EPIDERMAL INTERACTIONS
Hair loss is mainly caused by hormones, autoimmune issues, and chemotherapy, and needs more research for treatments.
research 880 Triptolide (TRP), a diterpenoid, shows a strong efficacy and a safe profile in the topical treatment of actinic keratosis lesions in a UV-B-induced mouse model
Triptolide effectively and safely reduces actinic keratosis lesions in mice.
research Biochemistry of skin in health and disease
Carruthers' work advances understanding of skin biochemistry but needs clearer interpretation and more discussion on certain topics.
research 54331 A meta-analysis of clinical trials evaluating the benefit of dermocosmetics on itch in AD patients associated with sensitive skin
Dermocosmetics significantly reduce itch and skin sensitivity in atopic dermatitis patients.
research Response to Keith et al. Re: “Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth and Tropism in a Randomized Clinical Trial”
research Keratins and disease at a glance
Keratins are crucial for tissue strength, and mutations in keratin genes can lead to various diseases, highlighting the need for targeted therapies.
research Lipid nanocosmeceuticals: a novel approach to skin therapy for anti-aging and skin disorders
Lipid-based nanocosmeceuticals improve skin therapy by enhancing ingredient delivery and effectiveness for anti-aging and skin disorders.
research Expression of retinoic acid receptors and dermal-epidermal interactions during mouse skin morphogenesis
Retinoic acid can change skin development, like turning scales into feathers or forming glands.
research Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme During the Hair Growth Cycle: Implications for Growth Control and Hair Follicle Transformations
Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.
research Platelet-Rich Plasma (PRP) in Dermatology: Cellular and Molecular Mechanisms of Action
PRP therapy helps skin heal and improve by promoting cell growth and repair.
research Dynamics and Epigenetics of the Epidermal Differentiation Complex
Epigenetic mechanisms control skin development by regulating gene expression.
research The Increasing Importance of the Hair Follicle Route in Dermal and Transdermal Drug Delivery
Using hair follicles can improve skin drug delivery.
research Assessment of the skin efficacy and acceptability of a cosmetic product in the treatment of the forearm hypertrichosis in female patients
The cosmetic product effectively reduced hair growth and thickness on forearms.
research Microneedle-Mediated Transdermal Drug Delivery for the Treatment of Multiple Skin Diseases
Microneedles improve drug delivery for skin diseases, enhancing treatment effectiveness and patient compliance.
research LB1077 Cutaneous responses to systemic iron: A potential role for epidermal turnover in mammalian iron excretion
Skin may help in getting rid of excess iron through the process of skin cell renewal.
research Pre-keratin isolated from epidermal microsomes
research Bioactive Small Molecule Enhances Skin Burn Wound Healing and Hair Follicle Regeneration by Activating PI3K/AKT Signaling Pathway: A Preclinical Evaluation in Animal Model
Shikonin, a small molecule, speeds up burn wound healing and hair growth by activating the PI3K/Akt pathway.
research Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives
Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
research Revisiting the significance of keratin expression in complex epithelia
Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.