883 citations
,
August 2016 in “Nature Reviews Disease Primers” Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.
467 citations
,
October 2014 in “European Journal of Endocrinology” The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.
269 citations
,
August 2002 in “Journal of The American Academy of Dermatology” 5% minoxidil works better for hair growth and density, with minor irritation.
251 citations
,
October 2014 in “The Journal of Clinical Endocrinology & Metabolism” The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
237 citations
,
January 2010 in “The Journal of Sexual Medicine” The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.
211 citations
,
May 2013 in “Journal of Nutrition Health & Aging” MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.
185 citations
,
February 2018 in “Journal of Investigative Dermatology” Melatonin may benefit skin health and could be a promising treatment in dermatology.
164 citations
,
April 2008 in “Cochrane library” Current treatments for alopecia show no significant long-term benefits.
151 citations
,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
140 citations
,
December 2017 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
120 citations
,
November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
117 citations
,
May 2017 in “Human Reproduction Update” The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
99 citations
,
July 2017 in “Clinical Reviews in Allergy & Immunology” New treatments for Alopecia Areata show promise but need to be more effective and affordable.
98 citations
,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
88 citations
,
May 2012 in “Human Reproduction Update” Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.
78 citations
,
June 2022 in “Infection” Many COVID-19 survivors experience long-term symptoms like fatigue and sleep issues, needing ongoing medical support.
66 citations
,
January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
61 citations
,
April 2014 in “Radiation Research” RTA 408 cream protects mice from radiation skin damage.
55 citations
,
September 2017 in “Journal of Cosmetic Dermatology” Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.
53 citations
,
July 2009 in “Journal of the American Academy of Dermatology” The study suggests smoking is common in HS patients but its role is unclear, and more research is needed to understand HS causes.
51 citations
,
July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
48 citations
,
October 2014 in “International Journal of Cardiology” People with alopecia are at higher risk for heart disease and have more heart-related risk factors.
44 citations
,
September 2015 in “Annals of Oncology” Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.
43 citations
,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
42 citations
,
September 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.
41 citations
,
November 2024 in “Molecular Biomedicine” Engineered extracellular vesicles show promise for targeted therapy but need more research for clinical use.
40 citations
,
August 2018 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
38 citations
,
March 2020 in “Current Hypertension Reports” Reproductive factors can increase hypertension risk and affect cardiovascular health.
38 citations
,
September 2019 in “Chinese Medical Journal” Using steroids can increase the risk of heart problems.
38 citations
,
September 2017 in “Oncologist” Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.