88 citations
,
September 2003 in “Clinical endocrinology” Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.
5 citations
,
November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
1 citations
,
June 2021 in “The Indonesian Biomedical Journal” Glycated hemoglobin is not as effective as the oral glucose tolerance test for diagnosing blood sugar problems in women with PCOS in Southern Iraq.
13 citations
,
March 2019 in “Physiological Research” Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.
May 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” DHEA therapy improved pubic hair growth and psychological well-being in young females with adrenal insufficiency.
2 citations
,
February 2005 in “Postgraduate obstetrics & gynecology” Certain medications can help treat PCOS symptoms, but they aren't FDA-approved for this use.
1 citations
,
November 2021 in “British Journal of Clinical Pharmacology” Saw palmetto may cause erectile dysfunction and needs better safety monitoring.
September 2025 in “Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi” Hormonal changes in women can worsen gum disease, so dentists and gynecologists should work together for early diagnosis and treatment.
1 citations
,
April 2013 in “PubMed” 14 citations
,
April 2024 in “The Journal of Steroid Biochemistry and Molecular Biology” 5α-reductases increase epitestosterone's effect on androgen receptors.
15 citations
,
May 2009 in “Steroids” Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.
23 citations
,
October 2008 in “Journal of medicinal chemistry” PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.
26 citations
,
November 2006 in “Pharmacology, Biochemistry and Behavior” Pregnancy reduces anxiety in rats, but finasteride reverses this effect.
January 2012 in “Medical Journal of Babylon” Spironolactone effectively treats hormonal acne, hair loss, and excess hair growth in women.
Women with androgenetic alopecia have normal levels of most blood steroids and binding proteins, but higher dehydroepiandrosterone. Some also have low "sex hormone-binding globulin" and "corticosteroide-binding globulin" capacity, and high "free androgen index" and "free cortisol index". Diane treatment can normalize these levels and improve hair conditions.
October 2015 in “Reactions Weekly” A woman got a scalp condition from using latanoprost, but it improved after stopping the drug and starting other treatments.
209 citations
,
March 1998 in “Biochemical and biophysical research communications” Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.
April 2019 in “Journal of the Endocrine Society” Androgens and estrogens are crucial for insulin secretion in males.
10 citations
,
May 2009 in “Sexual and Relationship Therapy” The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.
April 2004 in “AWHONN Lifelines” Hormonal contraception likely doesn't cause significant weight gain.
1 citations
,
September 2023 in “AACE clinical case reports” Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.
7 citations
,
August 1985 in “British journal of dermatology/British journal of dermatology, Supplement” Medroxyprogesterone acetate injections are more effective than topical ointment in treating excessive hair growth in women.
January 2019 in “Oncogen” Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
August 2022 in “Indonesian Journal of Medical Chemistry and Bioinformatics” Certain herbal compounds might help prevent hair loss in menopausal women by activating Vitamin D receptors.
35 citations
,
January 2005 in “Brain Research” Progesterone's anesthetic effects don't rely on progesterone receptors.
October 2004 in “Australian Prescriber” Lifestyle changes are more effective than medication for reducing type 2 diabetes risk.
Diane and Androcur 10 improved acne and seborrhea in most women, and hirsutism and alopecia in about half.