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The study concludes that the EDA2R gene is activated by p53 during chemotherapy but is not necessary for chemotherapy-induced hair loss.

MEGA PROTAC improves prediction and ranking of protein complexes better than existing methods.

Overexpression of SSAT in mice causes hair loss, liver damage, and sensitivity to polyamine analogues.

Corin helps control salt and sweat release in sweat glands.

TCDD changes skin cell growth and keratin production in mice.

A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Henna ointment may help reduce itching and improve wound healing in patients with epidermolysis bullosa.

Keratin 10 end domains may increase skin cancer risk by reducing cell death.

Antizyme reduces tumor growth and normalizes skin cell development affected by MEK.

CDP is crucial for lung and hair follicle cell development.

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Ulcerative colitis involves immune activation, chronic inflammation, and metabolic issues, some of which persist even during remission.

The protein called small nuclear ribonucleoprotein polypeptide E is identified as a cause of a type of hair loss without other symptoms.

Blocking certain pathways with kinase inhibitors may help treat cutaneous lupus erythematosus.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Blocking IL-8 can reduce skin rashes from cancer treatment.

uPA helps hair follicle cells grow.

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

Toll-like receptor 3 helps repair the skin barrier after UV damage.

Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.

High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.

Polygoni Cuspidati Rhizoma et Radix contains compounds that inhibit certain enzymes.

Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

Vitamin D receptor helps prevent skin tumors.

Deuruxolitinib effectively improves hair regrowth in alopecia areata but requires monitoring for side effects.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.